RPS2 of Arabidopsis thaliana: A leucine-rich repeat class of plant disease resistance genes

Andrew F. Bent; Barbara N. Kunkel; Douglas Dahlbeck; Kit L. Brown; Renate Schmidt; Jerome Giraudat; Jeffrey Leung; Brian J. Staskawicz

doi:10.1126/science.8091210

RPS2 of Arabidopsis thaliana: A leucine-rich repeat class of plant disease resistance genes

Andrew F. Bent, Barbara N. Kunkel, Douglas Dahlbeck, Kit L. Brown, Renate Schmidt, Jerome Giraudat, Jeffrey Leung, Brian J. Staskawicz

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771 Scopus citations

Abstract

Plant disease resistance genes function in highly specific pathogen recognition pathways. RPS2 is a resistance gene of Arabidopsis thaliana that confers resistance against Pseudomonas syringae bacteria that express a virulence gene avrRpt2. RPS2 was isolated by the use of a positional cloning strategy. The derived amino acid sequence of RPS2 contains leucine-rich repeat, membrane-spanning, leucine zipper, and P loop domains. The function of the RPS2 gene product in defense signal transduction is postulated to involve nucleotide triphosphate binding and protein-protein interactions and may also involve the reception of an elicitor produced by the avirulent pathogen.

Original language	English
Pages (from-to)	1856-1860
Number of pages	5
Journal	Science
Volume	265
Issue number	5180
DOIs	https://doi.org/10.1126/science.8091210
State	Published - Sep 23 1994

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abstract = "Plant disease resistance genes function in highly specific pathogen recognition pathways. RPS2 is a resistance gene of Arabidopsis thaliana that confers resistance against Pseudomonas syringae bacteria that express a virulence gene avrRpt2. RPS2 was isolated by the use of a positional cloning strategy. The derived amino acid sequence of RPS2 contains leucine-rich repeat, membrane-spanning, leucine zipper, and P loop domains. The function of the RPS2 gene product in defense signal transduction is postulated to involve nucleotide triphosphate binding and protein-protein interactions and may also involve the reception of an elicitor produced by the avirulent pathogen.",

author = "Bent, {Andrew F.} and Kunkel, {Barbara N.} and Douglas Dahlbeck and Brown, {Kit L.} and Renate Schmidt and Jerome Giraudat and Jeffrey Leung and Staskawicz, {Brian J.}",

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AU - Kunkel, Barbara N.

AU - Dahlbeck, Douglas

AU - Brown, Kit L.

AU - Schmidt, Renate

AU - Giraudat, Jerome

AU - Leung, Jeffrey

AU - Staskawicz, Brian J.

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AB - Plant disease resistance genes function in highly specific pathogen recognition pathways. RPS2 is a resistance gene of Arabidopsis thaliana that confers resistance against Pseudomonas syringae bacteria that express a virulence gene avrRpt2. RPS2 was isolated by the use of a positional cloning strategy. The derived amino acid sequence of RPS2 contains leucine-rich repeat, membrane-spanning, leucine zipper, and P loop domains. The function of the RPS2 gene product in defense signal transduction is postulated to involve nucleotide triphosphate binding and protein-protein interactions and may also involve the reception of an elicitor produced by the avirulent pathogen.

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RPS2 of Arabidopsis thaliana: A leucine-rich repeat class of plant disease resistance genes

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