RPL-6: An Achilles Needle in the Malaria Haystack?

Lisa L. Drewry; John T. Harty

doi:10.1016/j.pt.2020.06.001

RPL-6: An Achilles Needle in the Malaria Haystack?

Lisa L. Drewry, John T. Harty

Department of Molecular Microbiology

Research output: Contribution to journal › Short survey › peer-review

Abstract

Malaria is a global health scourge for which a highly effective vaccine remains frustratingly elusive. Recent identification of an endogenous malaria antigen that stimulates robust T_RM-mediated immunity in mice by Valencia-Hernandez et al. strengthens the case for prime-and-trap malaria vaccines and will greatly aid further investigations of cellular antimalarial immunity.

Original language	English
Pages (from-to)	651-653
Number of pages	3
Journal	Trends in Parasitology
Volume	36
Issue number	8
DOIs	https://doi.org/10.1016/j.pt.2020.06.001
State	Published - Aug 2020

Keywords

liver
malaria
T
vaccine

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10.1016/j.pt.2020.06.001

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title = "RPL-6: An Achilles Needle in the Malaria Haystack?",

abstract = "Malaria is a global health scourge for which a highly effective vaccine remains frustratingly elusive. Recent identification of an endogenous malaria antigen that stimulates robust TRM-mediated immunity in mice by Valencia-Hernandez et al. strengthens the case for prime-and-trap malaria vaccines and will greatly aid further investigations of cellular antimalarial immunity.",

keywords = "liver, malaria, T, vaccine",

author = "Drewry, {Lisa L.} and Harty, {John T.}",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = aug,

doi = "10.1016/j.pt.2020.06.001",

language = "English",

volume = "36",

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journal = "Trends in Parasitology",

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T2 - An Achilles Needle in the Malaria Haystack?

AU - Drewry, Lisa L.

AU - Harty, John T.

PY - 2020/8

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N2 - Malaria is a global health scourge for which a highly effective vaccine remains frustratingly elusive. Recent identification of an endogenous malaria antigen that stimulates robust TRM-mediated immunity in mice by Valencia-Hernandez et al. strengthens the case for prime-and-trap malaria vaccines and will greatly aid further investigations of cellular antimalarial immunity.

AB - Malaria is a global health scourge for which a highly effective vaccine remains frustratingly elusive. Recent identification of an endogenous malaria antigen that stimulates robust TRM-mediated immunity in mice by Valencia-Hernandez et al. strengthens the case for prime-and-trap malaria vaccines and will greatly aid further investigations of cellular antimalarial immunity.

KW - liver

KW - malaria

KW - T

KW - vaccine

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U2 - 10.1016/j.pt.2020.06.001

DO - 10.1016/j.pt.2020.06.001

M3 - Short survey

C2 - 32565051

AN - SCOPUS:85086508146

SN - 1471-4922

VL - 36

SP - 651

EP - 653

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 8

ER -

RPL-6: An Achilles Needle in the Malaria Haystack?

Abstract

Keywords

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