TY - JOUR
T1 - Round window electrocochleography and speech perception outcomes in adult cochlear implant subjects
T2 - Comparison with audiometric and biographical information
AU - McClellan, Joseph H.
AU - Formeister, Eric J.
AU - Merwin, William H.
AU - Dillon, Margaret T.
AU - Calloway, Nathan
AU - Iseli, Claire
AU - Buchman, Craig A.
AU - Fitzpatrick, Douglas C.
AU - Adunka, Oliver F.
N1 - Publisher Copyright:
© 2014 Otology & Neurotology, Inc.
PY - 2014
Y1 - 2014
N2 - Hypothesis: Intraoperative round window (RW) electrocochleography (ECoG) can help predict speech perception outcomes in adult cochlear implant (CI) recipients.Background: Speech perception outcomes using CIs are highly variable. Recent data demonstrated that intraoperative ECoG could account for nearly half the variance in postoperative word scores. The present study seeks to update this correlation with a larger sample size and determine if addition of clinical variables improves the prediction.Methods: Intraoperative RW ECoG was performed in adult subjects undergoing CI. Amplitudes of the ongoing response to tone bursts of multiple frequencies at 85 to 95 dB HL were summed to obtain the total response (ECoG-TR). ECoG-TR was correlated with postoperative speech perception scores. Multiple linear regression was used to combine clinical factors with the ECoG-TR.Results: The ECoG-TR accounted for 40% of the variance in CNC word scores (n = 32). The preoperative pure tone average (PTA) was the only clinical factor with a significant correlation (r2 = 20%). The ability to predict word scores using ECoG-TR and PTA, or after addition of age and duration of hearing loss, was not significantly different from using ECoG-TR alone. For 2 outliers, ECoG-TR predicted a better word score than obtained.Conclusions: The measurement of cochlear physiology before CI, reduced to a single variable, is a better predictor of postoperative speech perception than common clinical factors. Additional analysis of the outliers showed that waveform morphology can provide distinct information in individual cases.
AB - Hypothesis: Intraoperative round window (RW) electrocochleography (ECoG) can help predict speech perception outcomes in adult cochlear implant (CI) recipients.Background: Speech perception outcomes using CIs are highly variable. Recent data demonstrated that intraoperative ECoG could account for nearly half the variance in postoperative word scores. The present study seeks to update this correlation with a larger sample size and determine if addition of clinical variables improves the prediction.Methods: Intraoperative RW ECoG was performed in adult subjects undergoing CI. Amplitudes of the ongoing response to tone bursts of multiple frequencies at 85 to 95 dB HL were summed to obtain the total response (ECoG-TR). ECoG-TR was correlated with postoperative speech perception scores. Multiple linear regression was used to combine clinical factors with the ECoG-TR.Results: The ECoG-TR accounted for 40% of the variance in CNC word scores (n = 32). The preoperative pure tone average (PTA) was the only clinical factor with a significant correlation (r2 = 20%). The ability to predict word scores using ECoG-TR and PTA, or after addition of age and duration of hearing loss, was not significantly different from using ECoG-TR alone. For 2 outliers, ECoG-TR predicted a better word score than obtained.Conclusions: The measurement of cochlear physiology before CI, reduced to a single variable, is a better predictor of postoperative speech perception than common clinical factors. Additional analysis of the outliers showed that waveform morphology can provide distinct information in individual cases.
KW - Auditory nerve neurophonic
KW - Cochlear electrophysiology
KW - Cochlear implant outcomes
KW - Cochlear microphonic
KW - Electrocochleography V Hearing preservation
KW - Intraoperative monitoring
KW - Prediction of outcomes
KW - Residual hearing
UR - http://www.scopus.com/inward/record.url?scp=84914152791&partnerID=8YFLogxK
U2 - 10.1097/MAO.0000000000000557
DO - 10.1097/MAO.0000000000000557
M3 - Article
C2 - 25118584
AN - SCOPUS:84914152791
SN - 1531-7129
VL - 35
SP - e245-e252
JO - Otology and Neurotology
JF - Otology and Neurotology
IS - 9
ER -