The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation, or positive selection of T cells.

Original languageEnglish
Pages (from-to)26-31
Number of pages6
JournalCurrent Opinion in Immunology
Issue number1
StatePublished - 1991


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