Role of MHC and antigens in T-cell development

Kenneth M. Murphy

doi:10.1016/0952-7915(91)90072-9

Role of MHC and antigens in T-cell development

Kenneth M. Murphy

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation, or positive selection of T cells.

Original language	English
Pages (from-to)	26-31
Number of pages	6
Journal	Current Opinion in Immunology
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/0952-7915(91)90072-9
State	Published - 1991

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title = "Role of MHC and antigens in T-cell development",

abstract = "The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation, or positive selection of T cells.",

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AB - The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation, or positive selection of T cells.

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DO - 10.1016/0952-7915(91)90072-9

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Role of MHC and antigens in T-cell development

Abstract

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