Role of Chemistry in Lead Discovery

Roland E. Dolle, Karin Worm

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

6 Scopus citations
Original languageEnglish
Title of host publicationLead Generation Approaches in Drug Discovery
PublisherJohn Wiley and Sons
Number of pages32
ISBN (Print)9780470257616
StatePublished - Jun 16 2010


  • Chemistry and its role in lead discovery
  • Early ADME property incorporation - mGluR1 antagonists
  • HTC, Hit finding and HTL case studies

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