Role of Chemistry in Lead Discovery

Roland E. Dolle, Karin Worm

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
Original languageEnglish
Title of host publicationLead Generation Approaches in Drug Discovery
PublisherJohn Wiley and Sons
Pages259-290
Number of pages32
ISBN (Print)9780470257616
DOIs
StatePublished - Jun 16 2010
Externally publishedYes

Keywords

  • Chemistry and its role in lead discovery
  • Early ADME property incorporation - mGluR1 antagonists
  • HTC, Hit finding and HTL case studies

Cite this

Dolle, R. E., & Worm, K. (2010). Role of Chemistry in Lead Discovery. In Lead Generation Approaches in Drug Discovery (pp. 259-290). John Wiley and Sons. https://doi.org/10.1002/9780470584170.ch9