Role for Serine Protease HtrA (DegP) of Streptococcus pyogenes in the Biogenesis of Virulence Factors SpeB and the Hemolysin Streptolysin S

Medicine & Life Sciences

• streptolysin S 100%
• Hemolysin Proteins 71%
• Streptococcus pyogenes 67%
• Serine Proteases 62%
• Virulence Factors 57%
• Enzyme Precursors 35%
• Cysteine Proteases 33%
• Sequence Deletion 31%
• Heat-Shock Response 30%
• Gram-Positive Bacteria 30%
• Gene Silencing 29%
• Streptococcus 28%
• Growth 27%
• Proteolysis 25%
• Virulence 24%
• Peptide Hydrolases 23%
• Chromosomes 21%
• Proteins 20%
• Phenotype 16%
• Mutation 15%
• Infections 13%

Agriculture & Biology

• streptolysin 86%
• Streptococcus pyogenes 73%
• hemolysins 66%
• serine proteinases 60%
• biogenesis 56%
• virulence 44%
• mutants 32%
• inactivation 22%
• sequence deletion 18%
• zymogens 17%
• pathogens 16%
• cysteine proteinases 15%
• thermal stress 15%
• protein degradation 14%
• Streptococcus 14%
• Gram-positive bacteria 14%
• animal models 12%
• proteinases 10%
• secretion 9%
• mutation 9%
• proteins 9%
• phenotype 9%
• chromosomes 8%
• organisms 7%
• infection 7%
• genes 4%