RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer

R. D. Church, J. Yu, J. W. Fleshman, W. D. Shannon, R. Govindan, H. L. McLeod

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Dukes' C tumours, and changes in Cox-1 expression may be of importance.

Original languageEnglish
Pages (from-to)1015-1018
Number of pages4
JournalBritish Journal of Cancer
Issue number6
StatePublished - Sep 13 2004


  • Colorectal cancer
  • Cyclooxygenase
  • Gene expression


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