@article{2478e1f8db1d4c1da81d5badb77b89e0,
title = "RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation",
abstract = "Reconstitution of stress granule assembly reveals an autoinhibitory conformation of G3BP that is alleviated by RNA binding, demonstrating how this central node of the stress granule network phase-separates in response to rising cellular RNA concentrations.",
keywords = "G3BP, Neurodegenerative disease, RNP granules, liquid-to-solid transition, phase separation, stress granules, stress response",
author = "Jordina Guill{\'e}n-Boixet and Andrii Kopach and Holehouse, {Alex S.} and Sina Wittmann and Marcus Jahnel and Raimund Schl{\"u}{\ss}ler and Kyoohyun Kim and Trussina, {Irmela R.E.A.} and Jie Wang and Daniel Mateju and Ina Poser and Shovamayee Maharana and Martine Ruer-Gru{\ss} and Doris Richter and Xiaojie Zhang and Chang, {Young Tae} and Jochen Guck and Alf Honigmann and Julia Mahamid and Hyman, {Anthony A.} and Pappu, {Rohit V.} and Simon Alberti and Franzmann, {Titus M.}",
note = "Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2020",
month = apr,
day = "16",
doi = "10.1016/j.cell.2020.03.049",
language = "English",
volume = "181",
pages = "346--361.e17",
journal = "Cell",
issn = "0092-8674",
number = "2",
}