TY - JOUR
T1 - Risk Stratification for Proven Acute Pulmonary Embolism
T2 - What Information Is Needed?
AU - Barrios, Deisy
AU - Yusen, Roger D.
AU - Jiménez, David
N1 - Publisher Copyright:
© Thieme Medical Publishers333 Seventh Avenue, New York, NY 10001, USA.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Classification of risk drives treatment decisions for patients with acute symptomatic pulmonary embolism (PE). High-risk patients with acute symptomatic PE have hemodynamic instability (i.e., shock or hypotension present), and treatment guidelines suggest systemically administered thrombolytic therapy in this setting. Normotensive PE patients at low risk for early complications (low-risk PE) might benefit from treatment at home or early discharge, while normotensive patients with preserved systemic arterial pressure deemed as having a high risk for PE-related adverse clinical events (intermediate-high-risk PE) might benefit from close observation and consideration of escalation of therapy. Prognostic tools (e.g., clinical prognostic scoring systems, imaging testing, and cardiac laboratory biomarkers) assist with the classification of patients into these categories.
AB - Classification of risk drives treatment decisions for patients with acute symptomatic pulmonary embolism (PE). High-risk patients with acute symptomatic PE have hemodynamic instability (i.e., shock or hypotension present), and treatment guidelines suggest systemically administered thrombolytic therapy in this setting. Normotensive PE patients at low risk for early complications (low-risk PE) might benefit from treatment at home or early discharge, while normotensive patients with preserved systemic arterial pressure deemed as having a high risk for PE-related adverse clinical events (intermediate-high-risk PE) might benefit from close observation and consideration of escalation of therapy. Prognostic tools (e.g., clinical prognostic scoring systems, imaging testing, and cardiac laboratory biomarkers) assist with the classification of patients into these categories.
KW - mortality
KW - prognosis
KW - pulmonary embolism
UR - http://www.scopus.com/inward/record.url?scp=85013231702&partnerID=8YFLogxK
U2 - 10.1055/s-0036-1597556
DO - 10.1055/s-0036-1597556
M3 - Article
C2 - 28208194
AN - SCOPUS:85013231702
SN - 1069-3424
VL - 38
SP - 11
EP - 17
JO - Seminars in Respiratory and Critical Care Medicine
JF - Seminars in Respiratory and Critical Care Medicine
IS - 1
M1 - 01229
ER -