TY - JOUR
T1 - Risk factors for peripherally inserted central catheter complications in neonates
AU - Pet, Gillian C.
AU - Eickhoff, Jens C.
AU - McNevin, Kate E.
AU - Do, Julie
AU - McAdams, Ryan M.
N1 - Publisher Copyright:
© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Objective: To determine factors associated with nonelective PICC removal and complications. Study design: Overall, 1234 PICCs were placed in 918 hospitalized infants <45 weeks postmenstrual age. Outcomes studied include nonelective PICC removal (removal prior to completion of therapy) and line complications. Univariate and multivariate mixed-effects logistic regression analyses were conducted to evaluate the associations between potential predictor variables and clinical outcomes Results: Nonelective PICC removal occurred in 28.4% and complications in 34.4% of infants. Nonelective removal (p < 0.001) and complications (p = 0.006) occurred more often with upper than lower extremity PICCs. Malposition in the first 72 h (p = 0.0009) and over time (p = 0.0003) were more common in upper extremity PICCS; however, upper extremity PICCs were associated with a decreased incidence of phlebitis, edema, and perfusion changes (p = 0.03). Conclusions: Approximately one-third of PICCs were associated with complications. When feasible, lower extremity PICCs should be placed as they may be associated with fewer complications.
AB - Objective: To determine factors associated with nonelective PICC removal and complications. Study design: Overall, 1234 PICCs were placed in 918 hospitalized infants <45 weeks postmenstrual age. Outcomes studied include nonelective PICC removal (removal prior to completion of therapy) and line complications. Univariate and multivariate mixed-effects logistic regression analyses were conducted to evaluate the associations between potential predictor variables and clinical outcomes Results: Nonelective PICC removal occurred in 28.4% and complications in 34.4% of infants. Nonelective removal (p < 0.001) and complications (p = 0.006) occurred more often with upper than lower extremity PICCs. Malposition in the first 72 h (p = 0.0009) and over time (p = 0.0003) were more common in upper extremity PICCS; however, upper extremity PICCs were associated with a decreased incidence of phlebitis, edema, and perfusion changes (p = 0.03). Conclusions: Approximately one-third of PICCs were associated with complications. When feasible, lower extremity PICCs should be placed as they may be associated with fewer complications.
UR - http://www.scopus.com/inward/record.url?scp=85077536709&partnerID=8YFLogxK
U2 - 10.1038/s41372-019-0575-7
DO - 10.1038/s41372-019-0575-7
M3 - Article
C2 - 31911643
AN - SCOPUS:85077536709
VL - 40
SP - 581
EP - 588
JO - Journal of Perinatology
JF - Journal of Perinatology
SN - 0743-8346
IS - 4
ER -