Risk factors for cancer-related distress in colorectal cancer survivors: one year post surgery

Claire J. Han, Biljana Gigic, Martin Schneider, Yakup Kulu, Anita R. Peoples, Jennifer Ose, Torsten Kölsch, Paul B. Jacobsen, Graham A. Colditz, Jane C. Figueiredo, William M. Grady, Christopher I. Li, David Shibata, Erin M. Siegel, Adetunji T. Toriola, Alexis B. Ulrich, Karen L. Syrjala, Cornelia M. Ulrich

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Purposes: Cancer-related distress is known to persist long after completion of treatment. Factors related to distress are largely unexplored in colorectal cancer (CRC) survivors. We examined changes over time and risk factors for distress in CRC patients over the first year after surgery. Methods: We included 212 CRC patients with data at 6 and 12 months post-surgery from the ColoCare Study in Heidelberg, Germany. Sociodemographic and lifestyle factors, social support, and health-related quality of life (HrQOL) prior to surgery were evaluated as predictors of cancer-related distress. Distress was measured with the Cancer and Treatment Distress instrument (CTXD). Linear regression analyses examined associations between risk factors and distress. Results: Distress subscale scores varied significantly over time: health burden subscale score increased (P <.001), while finances (P =.004), medical demands (P <.001), and identity (P <.001) subscale scores decreased over time. Uncertainty and family strain subscale scores did not change. Younger age, lower income, advanced tumor stage, poorer social support, and poorer baseline HrQOL predicted higher level distress at 6 and 12 months. Conclusion: Cancer-related distress continues unresolved after surgery. Although some risk factors are difficult to alter, those at highest risk can be identified earlier for possible preventive strategies. Implications for Cancer Survivors: Screening for risk factors pre-surgery would allow for targeted interventions including strategies to improve resources for those with low support, thereby reducing long-term distress in CRC survivors.

Original languageEnglish
Pages (from-to)305-315
Number of pages11
JournalJournal of Cancer Survivorship
Volume14
Issue number3
DOIs
StatePublished - Jun 1 2020

Keywords

  • Cancer
  • Clinical management
  • Colorectal neoplasms
  • Distress
  • Quality of life
  • Surgical oncology

Fingerprint

Dive into the research topics of 'Risk factors for cancer-related distress in colorectal cancer survivors: one year post surgery'. Together they form a unique fingerprint.

Cite this