TY - JOUR
T1 - Right ventricular ejection fraction measured by first-pass intravenous krypton-81m
T2 - Reproducibility and comparison with technetium-99m
AU - Wong, Dean F.
AU - Natarajan, T. K.
AU - Summer, Warren
AU - Tibbits, Paul A.
AU - Beck, Thomas
AU - Koller, Daniel
AU - Kasecamp, Wayne
AU - Lamb, James
AU - Olynyk, Joseph
AU - Philp, Mary Sue
AU - Bryan, Marshall
AU - Wagner, Henry N.
N1 - Funding Information:
From The Johns Hopkins Medical Institutions, Baltimore, Maryland. This study was supported in part by grant CA 32845 from the U.S. Public Health Service, Bethesda, Maryland. Manuscript received May 30, 1984; revised manuscript received May 7, 1985, accepted May 8, 1985.
PY - 1985/11/1
Y1 - 1985/11/1
N2 - Study of the effects of various diseases and therapeutic manipulation of pulmonary vascular resistance on the right ventricle has been restricted by methodologic limitations. The radioactive gas in solution, krypton-81m was used to study the right ventricle and the technique was compared with a technetium-99m method. In 22 subjects, first-pass krypton-81m right ventricular ejection fraction, acquired both in list mode and electrocardiogramgated frame mode, correlated well (r = 0.81 and 0.86, respectively, p < 0.01) with that determined by technetium-99m first-pass studies over a broad range of ventricular function. The reproducibility of the technique was excellent (r = 0.84 and 0.95 for each acquisition mode, respectively). Krypton-81m first-pass studies provide accurate and reproducible estimates of right ventricular function. Use of krypton allows multiple measurements, with or without perturbations, over a short period of time.
AB - Study of the effects of various diseases and therapeutic manipulation of pulmonary vascular resistance on the right ventricle has been restricted by methodologic limitations. The radioactive gas in solution, krypton-81m was used to study the right ventricle and the technique was compared with a technetium-99m method. In 22 subjects, first-pass krypton-81m right ventricular ejection fraction, acquired both in list mode and electrocardiogramgated frame mode, correlated well (r = 0.81 and 0.86, respectively, p < 0.01) with that determined by technetium-99m first-pass studies over a broad range of ventricular function. The reproducibility of the technique was excellent (r = 0.84 and 0.95 for each acquisition mode, respectively). Krypton-81m first-pass studies provide accurate and reproducible estimates of right ventricular function. Use of krypton allows multiple measurements, with or without perturbations, over a short period of time.
UR - http://www.scopus.com/inward/record.url?scp=0022342139&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(85)91135-X
DO - 10.1016/0002-9149(85)91135-X
M3 - Article
C2 - 4061301
AN - SCOPUS:0022342139
SN - 0002-9149
VL - 56
SP - 776
EP - 780
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 12
ER -