TY - JOUR
T1 - Revisiting the relationship between neural correlates of sensory gating and self-reported sensory gating inventory
T2 - An MEG investigation
AU - Jian, Jun Rui
AU - Lin, Yen Yun
AU - Connor, Lisa Tabor
AU - Cheng, Chia Hsiung
N1 - Funding Information:
This work was supported by Chang Gung Memorial Hospital (CMRPD1K0061, CMRPD1K0581), Healthy Aging Research Center, Chang Gung University from the Featured Areas Research Center Program within the Framework of the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan (EMRPD1K0431), and Ministry of Science and Technology (MOST-108-2628-B-182-002, MOST-109-2628-B-182-012, MOST-110-2628-B-182-010).
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Background: Accumulated evidence has revealed that bilateral superior temporal gyrus (STG), inferior frontal gyrus (IFG), and inferior parietal lobule (IPL) are involved in the processes of sensory gating (SG). However, it remains unknown which neural correlate(s) of SG specifically reflect individuals’ perceptual experiences, as measured by the Sensory Gating Inventory (SGI). Thus, this study aims to investigate the relationship of SGI with cortical SG-related regions. Furthermore, we examine whether SG hemispheric asymmetry exists, which is still an inconclusive issue. Methods: Twenty-two healthy young adults performed the auditory paired-stimulus paradigm during magnetoencephalographic recordings. SG of M50 and M100 was measured as ratios (S2/S1) and differences (S1–S2). They were also evaluated with SGI, which factored into three categories of Perceptual Modulation, Distractibility, and Over-Inclusion. SG in the STG, IFG, and IPL were compared between left and right hemispheres, and were used to determine the relationship with SGI. Results: Only M100 SG differences (S1–S2) of the right IFG were significantly correlated with scores of Perceptual Modulation (partial r = -0.392, p = 0.040) and total SGI scores (partial r = -0.387, p = 0.041). However, we did not find significant lateralization of M50 SG and M100 SG in any studying region. Conclusions: The individual's perceptual experience is specifically related to electrophysiological SG function of the right IFG.
AB - Background: Accumulated evidence has revealed that bilateral superior temporal gyrus (STG), inferior frontal gyrus (IFG), and inferior parietal lobule (IPL) are involved in the processes of sensory gating (SG). However, it remains unknown which neural correlate(s) of SG specifically reflect individuals’ perceptual experiences, as measured by the Sensory Gating Inventory (SGI). Thus, this study aims to investigate the relationship of SGI with cortical SG-related regions. Furthermore, we examine whether SG hemispheric asymmetry exists, which is still an inconclusive issue. Methods: Twenty-two healthy young adults performed the auditory paired-stimulus paradigm during magnetoencephalographic recordings. SG of M50 and M100 was measured as ratios (S2/S1) and differences (S1–S2). They were also evaluated with SGI, which factored into three categories of Perceptual Modulation, Distractibility, and Over-Inclusion. SG in the STG, IFG, and IPL were compared between left and right hemispheres, and were used to determine the relationship with SGI. Results: Only M100 SG differences (S1–S2) of the right IFG were significantly correlated with scores of Perceptual Modulation (partial r = -0.392, p = 0.040) and total SGI scores (partial r = -0.387, p = 0.041). However, we did not find significant lateralization of M50 SG and M100 SG in any studying region. Conclusions: The individual's perceptual experience is specifically related to electrophysiological SG function of the right IFG.
KW - Frontal cortex
KW - Hemispheric asymmetry
KW - Magnetoencephalography (MEG)
KW - Sensory Gating Inventory (SGI)
KW - Sensory gating (SG)
UR - http://www.scopus.com/inward/record.url?scp=85118839625&partnerID=8YFLogxK
U2 - 10.1016/j.neulet.2021.136336
DO - 10.1016/j.neulet.2021.136336
M3 - Article
C2 - 34758341
AN - SCOPUS:85118839625
SN - 0304-3940
VL - 766
JO - Neuroscience Letters
JF - Neuroscience Letters
M1 - 136336
ER -