Reversal of mortality for congenital diaphragmatic hernia with ECMO

K. Heiss; P. Manning; K. T. Oldham; A. G. Coran; T. Z. Polley; J. R. Wesley; R. H. Bartlett

doi:10.1097/00000658-198902000-00014

Reversal of mortality for congenital diaphragmatic hernia with ECMO

K. Heiss, P. Manning, K. T. Oldham, A. G. Coran, T. Z. Polley, J. R. Wesley, R. H. Bartlett

Department of Surgery

Research output: Contribution to journal › Review article › peer-review

99 Scopus citations

Abstract

Fifty infants with congenital diaphragmatic hernia symptomatic during the first hour of life were treated between June 1974 and December 1987. The introduction of ECMO in 1981, along with improved neonatal intensive care, was followed by an improvement in survival (from 50% to 76%) within this period. Of the ECMO era patients who failed conventional therapy and had an expected mortality of 80-100%, 13 of 15 (87%) survived, thus reversing the expected mortality. This indicates that ECMO is a successful, reliable, and safe method of pulmonary support for selected critically ill infants with congenital diaphragmatic hernia.

Original language	English
Pages (from-to)	225-230
Number of pages	6
Journal	Annals of surgery
Volume	209
Issue number	2
DOIs	https://doi.org/10.1097/00000658-198902000-00014
State	Published - 1989

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title = "Reversal of mortality for congenital diaphragmatic hernia with ECMO",

abstract = "Fifty infants with congenital diaphragmatic hernia symptomatic during the first hour of life were treated between June 1974 and December 1987. The introduction of ECMO in 1981, along with improved neonatal intensive care, was followed by an improvement in survival (from 50% to 76%) within this period. Of the ECMO era patients who failed conventional therapy and had an expected mortality of 80-100%, 13 of 15 (87%) survived, thus reversing the expected mortality. This indicates that ECMO is a successful, reliable, and safe method of pulmonary support for selected critically ill infants with congenital diaphragmatic hernia.",

author = "K. Heiss and P. Manning and Oldham, {K. T.} and Coran, {A. G.} and Polley, {T. Z.} and Wesley, {J. R.} and Bartlett, {R. H.}",

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AU - Heiss, K.

AU - Manning, P.

AU - Oldham, K. T.

AU - Coran, A. G.

AU - Polley, T. Z.

AU - Wesley, J. R.

AU - Bartlett, R. H.

PY - 1989

Y1 - 1989

N2 - Fifty infants with congenital diaphragmatic hernia symptomatic during the first hour of life were treated between June 1974 and December 1987. The introduction of ECMO in 1981, along with improved neonatal intensive care, was followed by an improvement in survival (from 50% to 76%) within this period. Of the ECMO era patients who failed conventional therapy and had an expected mortality of 80-100%, 13 of 15 (87%) survived, thus reversing the expected mortality. This indicates that ECMO is a successful, reliable, and safe method of pulmonary support for selected critically ill infants with congenital diaphragmatic hernia.

AB - Fifty infants with congenital diaphragmatic hernia symptomatic during the first hour of life were treated between June 1974 and December 1987. The introduction of ECMO in 1981, along with improved neonatal intensive care, was followed by an improvement in survival (from 50% to 76%) within this period. Of the ECMO era patients who failed conventional therapy and had an expected mortality of 80-100%, 13 of 15 (87%) survived, thus reversing the expected mortality. This indicates that ECMO is a successful, reliable, and safe method of pulmonary support for selected critically ill infants with congenital diaphragmatic hernia.

UR - http://www.scopus.com/inward/record.url?scp=0024502360&partnerID=8YFLogxK

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M3 - Review article

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VL - 209

SP - 225

EP - 230

JO - Annals of Surgery

JF - Annals of Surgery

IS - 2

ER -

Reversal of mortality for congenital diaphragmatic hernia with ECMO

Abstract

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