Reversal of mortality for congenital diaphragmatic hernia with ECMO

K. Heiss, P. Manning, K. T. Oldham, A. G. Coran, T. Z. Polley, J. R. Wesley, R. H. Bartlett

Research output: Contribution to journalReview articlepeer-review

104 Scopus citations


Fifty infants with congenital diaphragmatic hernia symptomatic during the first hour of life were treated between June 1974 and December 1987. The introduction of ECMO in 1981, along with improved neonatal intensive care, was followed by an improvement in survival (from 50% to 76%) within this period. Of the ECMO era patients who failed conventional therapy and had an expected mortality of 80-100%, 13 of 15 (87%) survived, thus reversing the expected mortality. This indicates that ECMO is a successful, reliable, and safe method of pulmonary support for selected critically ill infants with congenital diaphragmatic hernia.

Original languageEnglish
Pages (from-to)225-230
Number of pages6
JournalAnnals of surgery
Issue number2
StatePublished - 1989


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