Retrospective analysis of intravertebral collateral enhancement in patients with central venous obstruction

F. Joseph Simeone, Debbie L. Bennett, Connie Y. Chang, Ambrose J. Huang, Susan V. Kattapuram, Miriam A. Bredella, Martin Torriani

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: To compare prevalence and patterns of intravertebral collateral enhancement in patients with and without central venous obstruction (CVO). Materials and methods: Chest CTs performed between 1/1/2000 and 12/15/2012 with reports containing terms indicating CVO were identified. All contrast enhanced CTs were examined for the presence of CVO and collateral venous pathways. If intravertebral collateral enhancement was present, the pattern was recorded as nodular, linear, or both. Results: In 209 suspected cases of CVO, 53 (25 %) were confirmed with obstruction and 156 (75 %) were without obstruction. In patients with CVO, 47 % (25/53) demonstrated collateral venous flow through an intravertebral marrow pathway compared to 5 % (8/156) of patients without CVO (P < 0.0001). The most common level of enhancement was the upper thoracic spine, involving only the vertebral body. Nodular, linear, and combined nodular-linear enhancement patterns were seen with similar frequency. Nodular intravertebral collateral enhancement was mistaken for sclerotic metastases in 33 % (3/9) of cases. Conclusion: Intravertebral collateral enhancement was seen in almost half the patients with CVO and when nodular enhancement is present, it is important to differentiate between metastatic lesions and enhancement related to CVO.

Original languageEnglish
Pages (from-to)163-168
Number of pages6
JournalSkeletal Radiology
Volume45
Issue number2
DOIs
StatePublished - Feb 1 2016

Keywords

  • Central venous obstruction
  • Collateral venous pathways
  • Intravertebral collateral enhancement
  • Vena cava obstruction

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