TY - JOUR
T1 - Retroperitoneal Fibrosis
AU - Scheel, Paul J.
AU - Feeley, Nancy
PY - 2013/5
Y1 - 2013/5
N2 - Retroperitoneal fibrosis (RPF) is a condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space, for which no standard diagnostic criteria exist. Historically, treatment has focused on relieving the obstruction with percutaneous or cystoscopic assisted placement of ureteral stents followed by more definitive resolution of ureteric obstruction with open or laparoscopic ureterolysis. However, over the past several years management has shifted from primarily a surgical approach to an immunosuppressive-based therapy aimed at modulation of the immune system. This review focuses on the recent advances in the classification, epidemiology, pathophysiology, pathology, imaging, and treatment of RPF.
AB - Retroperitoneal fibrosis (RPF) is a condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space, for which no standard diagnostic criteria exist. Historically, treatment has focused on relieving the obstruction with percutaneous or cystoscopic assisted placement of ureteral stents followed by more definitive resolution of ureteric obstruction with open or laparoscopic ureterolysis. However, over the past several years management has shifted from primarily a surgical approach to an immunosuppressive-based therapy aimed at modulation of the immune system. This review focuses on the recent advances in the classification, epidemiology, pathophysiology, pathology, imaging, and treatment of RPF.
KW - Chronic periaortitis
KW - Management
KW - Retroperitoneal fibrosis
KW - Review
UR - http://www.scopus.com/inward/record.url?scp=84876713761&partnerID=8YFLogxK
U2 - 10.1016/j.rdc.2013.02.004
DO - 10.1016/j.rdc.2013.02.004
M3 - Review article
C2 - 23597969
AN - SCOPUS:84876713761
SN - 0889-857X
VL - 39
SP - 365
EP - 381
JO - Rheumatic Disease Clinics of North America
JF - Rheumatic Disease Clinics of North America
IS - 2
ER -