Retinal pharmacology: Inner retinal layers

P. D. Lukasiewicz

doi:10.1016/B978-008045046-9.00903-7

Retinal pharmacology: Inner retinal layers

P. D. Lukasiewicz

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

The retina is a layered structure with well-characterized neuronal cell types and circuits. The inner retina is the site of complex synaptic processing. These synaptic interactions occur at the inner plexiform layer (IPL), the second retinal synaptic layer, and mediate the temporal and spatial visual processing. A diversity of neurotransmitters and neuromodulators, released in the IPL, interact with a variety of receptors that can shape the visually evoked signal. This article reviews the pharmacology of the fast excitatory and the fast inhibitory synaptic mechanisms, as well as the neuromodulators that mediate visual processing in the inner retina.

Original language	English
Title of host publication	Encyclopedia of Neuroscience
Publisher	Elsevier Ltd
Pages	255-261
Number of pages	7
ISBN (Print)	9780080450469
DOIs	https://doi.org/10.1016/B978-008045046-9.00903-7
State	Published - 2009

Keywords

AMPA
Acetylcholine
Dopamine
GABA
Glutamate
Glutamate transporter
Glycine
Inner plexiform layer
Kainite
NMDA
Neuropeptide
Retina
Spillover

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10.1016/B978-008045046-9.00903-7

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title = "Retinal pharmacology: Inner retinal layers",

abstract = "The retina is a layered structure with well-characterized neuronal cell types and circuits. The inner retina is the site of complex synaptic processing. These synaptic interactions occur at the inner plexiform layer (IPL), the second retinal synaptic layer, and mediate the temporal and spatial visual processing. A diversity of neurotransmitters and neuromodulators, released in the IPL, interact with a variety of receptors that can shape the visually evoked signal. This article reviews the pharmacology of the fast excitatory and the fast inhibitory synaptic mechanisms, as well as the neuromodulators that mediate visual processing in the inner retina.",

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AB - The retina is a layered structure with well-characterized neuronal cell types and circuits. The inner retina is the site of complex synaptic processing. These synaptic interactions occur at the inner plexiform layer (IPL), the second retinal synaptic layer, and mediate the temporal and spatial visual processing. A diversity of neurotransmitters and neuromodulators, released in the IPL, interact with a variety of receptors that can shape the visually evoked signal. This article reviews the pharmacology of the fast excitatory and the fast inhibitory synaptic mechanisms, as well as the neuromodulators that mediate visual processing in the inner retina.

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KW - Acetylcholine

KW - Dopamine

KW - GABA

KW - Glutamate

KW - Glutamate transporter

KW - Glycine

KW - Inner plexiform layer

KW - Kainite

KW - NMDA

KW - Neuropeptide

KW - Retina

KW - Spillover

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SN - 9780080450469

SP - 255

EP - 261

BT - Encyclopedia of Neuroscience

PB - Elsevier Ltd

ER -

Retinal pharmacology: Inner retinal layers

Abstract

Keywords

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