Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD-Disease Outcome and Response to Therapy

Bram Verstockt, Nurulamin M. Noor, Urko M. Marigorta, Polychronis Pavlidis, Parakkal Deepak, Ryan C. Ungaro, Claudio Fiocchi, Joana Torres, Michael Scharl

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Inflammatory bowel diseases [IBD] are a heterogeneous spectrum with two extreme phenotypes, Crohn's disease [CD] and ulcerative colitis [UC], which both represent numerous phenotypical variations. Hence, we should no longer approach all IBD patients similarly, but rather aim to rethink clinical classifications and modify treatment algorithms to usher in a new era of precision medicine in IBD. This scientific ECCO workshop aims to provide a state-of-the-art overview on prognostic and predictive markers, shed light on key questions in biomarker development, propose best practices in IBD biomarker development [including trial design], and discuss the potential for multi-omic data integration to help drive further advances to make precision medicine a reality in IBD.

Original languageEnglish
Pages (from-to)1431-1442
Number of pages12
JournalJournal of Crohn's and Colitis
Volume15
Issue number9
DOIs
StatePublished - Sep 1 2021

Keywords

  • Precision medicine
  • disease outcome
  • disease prognosis
  • inflammatory bowel diseases
  • personalised medicine
  • response to therapy

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