TY - JOUR
T1 - Results of elective repair at 6 months or younger in 277 patients with tetralogy of Fallot
T2 - A 14-year experience at a single center
AU - Kirsch, Roxanne E.
AU - Glatz, Andrew C.
AU - Gaynor, J. William
AU - Nicolson, Susan C.
AU - Spray, Thomas L.
AU - Wernovsky, Gil
AU - Bird, Geoffrey L.
PY - 2014/2
Y1 - 2014/2
N2 - Objective: To report practice and outcomes in infants undergoing elective repair of tetralogy of Fallot. Methods: A review of a retrospective cohort of elective complete repair of infants age 6 months or younger from 1995 to 2009 was performed. Patients were excluded because of previous interventions, hypercyanotic episodes, intensive care admissions, additional major cardiac defects, or if they were not discharged after birth. Length of stay, mortality, and complications were recorded. Association was determined using logistic or linear regression models and univariate testing determined the multivariate model. Results: There were 277 patients included. The hospital mortality rate was zero. A total of 87.4% of patients were discharged home within 7 days of repair, and 21.6% of patients were discharged on or before the third postoperative day. The postoperative course was uncomplicated in 245 patients (88.4%). Longer support time was associated independently with increased odds of complications (P <.001). Longer support time, younger age, chromosomal abnormality, and presence of a complication were associated independently with a longer hospital stay (all P <.001). Patients younger than 3 months (n = 110) had a longer median hospital stay (4 vs 3 days; P <.001) and longer support times (77.3 ± 35.1 min vs 66.4 ± 34 min; P <.01). Conclusions: Elective tetralogy of Fallot repair was performed at 6 months or younger with low morbidity, no hospital mortality, and an 11.6% complication rate. Longer support times, lower weight, chromosomal abnormalities, and complications were associated with a significantly increased duration of hospital stay.
AB - Objective: To report practice and outcomes in infants undergoing elective repair of tetralogy of Fallot. Methods: A review of a retrospective cohort of elective complete repair of infants age 6 months or younger from 1995 to 2009 was performed. Patients were excluded because of previous interventions, hypercyanotic episodes, intensive care admissions, additional major cardiac defects, or if they were not discharged after birth. Length of stay, mortality, and complications were recorded. Association was determined using logistic or linear regression models and univariate testing determined the multivariate model. Results: There were 277 patients included. The hospital mortality rate was zero. A total of 87.4% of patients were discharged home within 7 days of repair, and 21.6% of patients were discharged on or before the third postoperative day. The postoperative course was uncomplicated in 245 patients (88.4%). Longer support time was associated independently with increased odds of complications (P <.001). Longer support time, younger age, chromosomal abnormality, and presence of a complication were associated independently with a longer hospital stay (all P <.001). Patients younger than 3 months (n = 110) had a longer median hospital stay (4 vs 3 days; P <.001) and longer support times (77.3 ± 35.1 min vs 66.4 ± 34 min; P <.01). Conclusions: Elective tetralogy of Fallot repair was performed at 6 months or younger with low morbidity, no hospital mortality, and an 11.6% complication rate. Longer support times, lower weight, chromosomal abnormalities, and complications were associated with a significantly increased duration of hospital stay.
UR - http://www.scopus.com/inward/record.url?scp=84892363926&partnerID=8YFLogxK
U2 - 10.1016/j.jtcvs.2013.03.033
DO - 10.1016/j.jtcvs.2013.03.033
M3 - Article
C2 - 23602127
AN - SCOPUS:84892363926
SN - 0022-5223
VL - 147
SP - 713
EP - 717
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
IS - 2
ER -