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Restoration of phagocyte function by interferon-γ in X-linked chronic granulomatous disease occurs at the level of a progenitor cell
R. A.B. Ezekowitz
, C. A. Sieff
, M. C. Dinauer
, D. G. Nathan
, S. H. Orkin
, P. E. Newburger
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Division of Hematology & Oncology
Rheumatic Diseases Research Resource-Based Center
DBBS - Molecular Cell Biology
DBBS - Immunology
DBBS - Molecular Microbiology and Microbial Pathogenesis
Research output
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Contribution to journal
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Article
›
peer-review
44
Scopus citations
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Keyphrases
Interferon-α (IFN-α)
100%
Progenitor Cells
100%
Superoxide
100%
X-linked Chronic Granulomatous Disease (X-CGD)
100%
Phagocyte Activity
100%
Nitroblue Tetrazolium
75%
Phagocytes
50%
Rare Cells
25%
Heavy Chain
25%
Prolonged Effect
25%
Daughter Cells
25%
Myeloid Progenitors
25%
Lymphokines
25%
Peripheral Blood
25%
In Vivo Applications
25%
Kindred
25%
Superoxide Production
25%
Cytochrome b
25%
Defective Genes
25%
Immunology and Microbiology
interferon
100%
Phagocyte
100%
Chronic Granulomatous Disease
100%
Superoxide
100%
Lymphokine
20%
Heavy Chain
20%
Myeloid Progenitor Cell
20%
Daughter Cell
20%
Cytochrome
20%
Neuroscience
Interferon
100%
Progenitor Cell
100%
Phagocyte
100%
Heavy Chain
25%
In Vivo
25%
Daughter Cell
25%
Myeloid
25%
Lymphokine
25%
Cytochrome B
25%