Resolution of Misleading COVID-19 Vaccination-Related Nodal and Splenic FDG Uptake in the Follow-up Study

Sudhir Bhimaniya; Amin Jahromi

doi:10.1097/RLU.0000000000004289

Resolution of Misleading COVID-19 Vaccination-Related Nodal and Splenic FDG Uptake in the Follow-up Study

Sudhir Bhimaniya, Amin Jahromi

Division of Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19 vaccination.

Original language	English
Pages (from-to)	E658-E659
Journal	Clinical nuclear medicine
Volume	47
Issue number	10
DOIs	https://doi.org/10.1097/RLU.0000000000004289
State	Published - Oct 2022

Keywords

COVID-19
FDG PET/CT
follow-up
immune response
lymph nodes
spleen
vaccination

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10.1097/RLU.0000000000004289

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title = "Resolution of Misleading COVID-19 Vaccination-Related Nodal and Splenic FDG Uptake in the Follow-up Study",

abstract = "Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19 vaccination.",

keywords = "COVID-19, FDG PET/CT, follow-up, immune response, lymph nodes, spleen, vaccination",

author = "Sudhir Bhimaniya and Amin Jahromi",

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year = "2022",

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N2 - Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19 vaccination.

AB - Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19 vaccination.

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Resolution of Misleading COVID-19 Vaccination-Related Nodal and Splenic FDG Uptake in the Follow-up Study

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Keywords

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