Resolution of Misleading COVID-19 Vaccination-Related Nodal and Splenic FDG Uptake in the Follow-up Study

Sudhir Bhimaniya, Amin Jahromi

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19 vaccination.

Original languageEnglish
Pages (from-to)E658-E659
JournalClinical nuclear medicine
Volume47
Issue number10
DOIs
StatePublished - Oct 2022

Keywords

  • COVID-19
  • FDG PET/CT
  • follow-up
  • immune response
  • lymph nodes
  • spleen
  • vaccination

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