Resistive training and chromium picolinate: Effects on inositols and liver and kidney functions in older adults

Wayne W. Campbell, Lyndon J.O. Joseph, Richard E. Ostlund, Richard A. Anderson, Peter A. Farrell, William J. Evans

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

This study assessed the effects of resistive training (RT) with or without chromium picolinate (Cr-pic) supplementation on the 24-h urinary excretions of myo-inositol, D-chiro-inositol, and pinitol, as well as clinical indices of kidney and liver functions. Thirty-two nondiabetic subjects, age 62 ± 4 y, performed RT twice weekly for 12 wk and consumed either 924 μg Cr/d as Cr-pic (n = 17) or a placebo (n = 15). Whole-body strength increased in all subjects by 20% and urinary chromium excretion increased 47-fold in the Cr-pic group. Urinary myo-inositol, D-chiro-inositol, and pinitol were not changed with RT or influenced by Cr-pic. Serum indices of kidney and liver functions were within clinically normal ranges at baseline and the end of the study. These results suggest that RT did not influence the urinary excretions of inositols. High dose Cr-pic did not influence the urinary excretion of inositols and the selected indices of kidney and liver functions in conjunction with RT.

Original languageEnglish
Pages (from-to)430-442
Number of pages13
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume14
Issue number4
DOIs
StatePublished - Aug 2004

Keywords

  • D-chiro-inositol
  • Insulin
  • Oral glucose tolerance test
  • Pinitol
  • Strength training

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