Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (19962007)

R. Douglas Wilson, Kerrie Lemerand, Mark P. Johnson, Alan W. Flake, Michael Bebbington, Holly L. Hedrick, N. Scott Adzick

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

Objective: The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated. Study Design: The retrospective review identified 93 women with OMFS from a single institution (1996-2007). Consent and questionnaires were sent to women. Institutional review board approval was obtained from the Committee for Protection of Human Subjects. Results: The total return rate was 57.3%. Total pregnancies reported were 47, with 36 delivering after 20 weeks' gestation. The uterine dehiscence and rupture rates were 14% and 14%, respectively. Fetal anomalies occurred in 4 subsequent pregnancies. Normal conception occurred in 98% of subsequent pregnancies. Gynecologic issues were reported by 8 women, with infertility, abdominal pain, and ovarian and uterine factors. Conclusion: The reproductive outcomes of uterine dehiscence (14%) and rupture (14%) in a subsequent pregnancy continue to be a major counseling issue for OMFS. Fertility and gynecologic factors do not appear to be increased for women undergoing OMFS.

Original languageEnglish
Pages (from-to)209.e1-209.e6
JournalAmerican journal of obstetrics and gynecology
Volume203
Issue number3
DOIs
StatePublished - Sep 2010

Keywords

  • fetal anomalies
  • in utero therapy
  • maternal-fetal surgery
  • maternal-fetal surgery risk
  • open maternal-fetal surgery outcomes
  • uterine dehiscence
  • uterine rupture

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