TY - JOUR
T1 - Reproducibility of resting cerebral blood flow measurements with H215O positron emission tomography in humans
AU - Matthew, Elizabeth
AU - Andreason, Paul
AU - Carson, Richard E.
AU - Herscovitch, Peter
AU - Pettigrew, Karen
AU - Cohen, Robert
AU - King, Catherine
AU - Johanson, Chris Ellyn
AU - Paul, Steven M.
PY - 1993
Y1 - 1993
N2 - Two consecutive measurements of resting CBF were carried out in normal volunteers (n = 25) using H215O positron emission tomography. Absolute whole-brain blood flow (WBBF; ml 100 g-1 min-1, mean ± SD) for the first (40.3 ± 6.4) and second (39.3 ± 6.5) measurements was not significantly different (mean % difference 2.3 ± 8.7). Analysis of regions of interest showed no significant differences in absolute regional CBF (rCBF) and normalized (rCBF/WBBF) rCBF. Left-right differences were also not significant. These data demonstrate the reproducibility of resting CBF measurements in normal humans.
AB - Two consecutive measurements of resting CBF were carried out in normal volunteers (n = 25) using H215O positron emission tomography. Absolute whole-brain blood flow (WBBF; ml 100 g-1 min-1, mean ± SD) for the first (40.3 ± 6.4) and second (39.3 ± 6.5) measurements was not significantly different (mean % difference 2.3 ± 8.7). Analysis of regions of interest showed no significant differences in absolute regional CBF (rCBF) and normalized (rCBF/WBBF) rCBF. Left-right differences were also not significant. These data demonstrate the reproducibility of resting CBF measurements in normal humans.
KW - Ho positron emission tomography
KW - Normalization of data
KW - Regions of interest
KW - Reproducibility of measurement
KW - Resting cerebral blood flow
UR - https://www.scopus.com/pages/publications/0027163503
U2 - 10.1038/jcbfm.1993.95
DO - 10.1038/jcbfm.1993.95
M3 - Article
C2 - 8360281
AN - SCOPUS:0027163503
SN - 0271-678X
VL - 13
SP - 748
EP - 754
JO - Journal of Cerebral Blood Flow and Metabolism
JF - Journal of Cerebral Blood Flow and Metabolism
IS - 5
ER -