TY - JOUR
T1 - Report of a pilot study of Cooling four preterm infants 32-35 weeks gestation with HIE
AU - Walsh, William F.
AU - Butler, David
AU - Schmidt, John W.
N1 - Publisher Copyright:
© 2015 - IOS Press and the authors. All rights reserved.
PY - 2015/5/18
Y1 - 2015/5/18
N2 - This report reviews the use of the Cool-Cap device to apply selective therapeutic hypothermia to the brain of preterm infants, without causing systemic hypothermia. Four infants, 32-35 weeks gestation, with suspected Hypoxic Ischemic Encephalopathy (HIE) received treatment aimed at providing selective brain cooling. It was not possible to apply cold circulating water to the scalp of the preterm infant without systemic hypothermia unless a warming blanket was also used. All infants had severe HIE and all had either death, or neurologic disability despite cooling attempts. Therapeutic hypothermia cannot be recommended at this time for preterm infants outside clinical trials.
AB - This report reviews the use of the Cool-Cap device to apply selective therapeutic hypothermia to the brain of preterm infants, without causing systemic hypothermia. Four infants, 32-35 weeks gestation, with suspected Hypoxic Ischemic Encephalopathy (HIE) received treatment aimed at providing selective brain cooling. It was not possible to apply cold circulating water to the scalp of the preterm infant without systemic hypothermia unless a warming blanket was also used. All infants had severe HIE and all had either death, or neurologic disability despite cooling attempts. Therapeutic hypothermia cannot be recommended at this time for preterm infants outside clinical trials.
KW - Hypoxic ischemic encephalopathy
KW - cool cap
KW - therapeutic hypothermia
UR - http://www.scopus.com/inward/record.url?scp=84930246780&partnerID=8YFLogxK
U2 - 10.3233/NPM-15814078
DO - 10.3233/NPM-15814078
M3 - Article
AN - SCOPUS:84930246780
SN - 1934-5798
VL - 8
SP - 47
EP - 51
JO - Journal of Neonatal-Perinatal Medicine
JF - Journal of Neonatal-Perinatal Medicine
IS - 1
ER -