Report of a pilot study of Cooling four preterm infants 32-35 weeks gestation with HIE

William F. Walsh, David Butler, John W. Schmidt

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

This report reviews the use of the Cool-Cap device to apply selective therapeutic hypothermia to the brain of preterm infants, without causing systemic hypothermia. Four infants, 32-35 weeks gestation, with suspected Hypoxic Ischemic Encephalopathy (HIE) received treatment aimed at providing selective brain cooling. It was not possible to apply cold circulating water to the scalp of the preterm infant without systemic hypothermia unless a warming blanket was also used. All infants had severe HIE and all had either death, or neurologic disability despite cooling attempts. Therapeutic hypothermia cannot be recommended at this time for preterm infants outside clinical trials.

Original languageEnglish
Pages (from-to)47-51
Number of pages5
JournalJournal of Neonatal-Perinatal Medicine
Volume8
Issue number1
DOIs
StatePublished - May 18 2015

Keywords

  • Hypoxic ischemic encephalopathy
  • cool cap
  • therapeutic hypothermia

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