Repeatability of Quantitative Brown Adipose Tissue Imaging Metrics on Positron Emission Tomography with 18F-Fluorodeoxyglucose in Humans

Tyler J. Fraum, John P. Crandall, Daniel R. Ludwig, Sihao Chen, Kathryn J. Fowler, Richard A. Laforest, Amber Salter, Farrokh Dehdashti, Hongyu An, Richard L. Wahl

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Utilizing a test-retest design and a modern cold-activation protocol, Fraum et al. show that BAT volume and SULmax are relatively stable across imaging sessions. These quantitative BAT metrics, which can be measured by either 18F-FDG-PET/CT or 18F-FDG-PET/MRI with excellent inter-reader reliability, are robust for tracking BAT activation longitudinally.

Original languageEnglish
Pages (from-to)212-224.e4
JournalCell metabolism
Volume30
Issue number1
DOIs
StatePublished - Jul 2 2019

Keywords

  • PET/CT
  • PET/MRI
  • brown adipose tissue
  • repeatability
  • test-retest

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