Repeatability of Quantitative Brown Adipose Tissue Imaging Metrics on Positron Emission Tomography with 18F-Fluorodeoxyglucose in Humans

Tyler J. Fraum; John P. Crandall; Daniel R. Ludwig; Sihao Chen; Kathryn J. Fowler; Richard A. Laforest; Amber Salter; Farrokh Dehdashti; Hongyu An; Richard L. Wahl

doi:10.1016/j.cmet.2019.05.019

Repeatability of Quantitative Brown Adipose Tissue Imaging Metrics on Positron Emission Tomography with ¹⁸F-Fluorodeoxyglucose in Humans

Tyler J. Fraum, John P. Crandall, Daniel R. Ludwig, Sihao Chen, Kathryn J. Fowler, Richard A. Laforest, Amber Salter, Farrokh Dehdashti, Hongyu An, Richard L. Wahl

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Utilizing a test-retest design and a modern cold-activation protocol, Fraum et al. show that BAT volume and SUL_max are relatively stable across imaging sessions. These quantitative BAT metrics, which can be measured by either ¹⁸F-FDG-PET/CT or ¹⁸F-FDG-PET/MRI with excellent inter-reader reliability, are robust for tracking BAT activation longitudinally.

Original language	English
Pages (from-to)	212-224.e4
Journal	Cell metabolism
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/j.cmet.2019.05.019
State	Published - Jul 2 2019

Keywords

PET/CT
PET/MRI
brown adipose tissue
repeatability
test-retest

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10.1016/j.cmet.2019.05.019

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Fraum, Tyler J. ; Crandall, John P. ; Ludwig, Daniel R. ; Chen, Sihao ; Fowler, Kathryn J. ; Laforest, Richard A. ; Salter, Amber ; Dehdashti, Farrokh ; An, Hongyu ; Wahl, Richard L. / Repeatability of Quantitative Brown Adipose Tissue Imaging Metrics on Positron Emission Tomography with ¹⁸F-Fluorodeoxyglucose in Humans. In: Cell metabolism. 2019 ; Vol. 30, No. 1. pp. 212-224.e4.

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abstract = "Utilizing a test-retest design and a modern cold-activation protocol, Fraum et al. show that BAT volume and SULmax are relatively stable across imaging sessions. These quantitative BAT metrics, which can be measured by either 18F-FDG-PET/CT or 18F-FDG-PET/MRI with excellent inter-reader reliability, are robust for tracking BAT activation longitudinally.",

keywords = "PET/CT, PET/MRI, brown adipose tissue, repeatability, test-retest",

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Repeatability of Quantitative Brown Adipose Tissue Imaging Metrics on Positron Emission Tomography with ¹⁸F-Fluorodeoxyglucose in Humans. / Fraum, Tyler J.; Crandall, John P.; Ludwig, Daniel R.; Chen, Sihao; Fowler, Kathryn J.; Laforest, Richard A.; Salter, Amber; Dehdashti, Farrokh ; An, Hongyu ; Wahl, Richard L.

In: Cell metabolism, Vol. 30, No. 1, 02.07.2019, p. 212-224.e4.

Research output: Contribution to journal › Article › peer-review

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