Repeat 2-stage exchange for infected total hip arthroplasty. A viable option?

S. M.Javad Mortazavi, Joseph T. O'Neil, Benjamin Zmistowski, Javad Parvizi, James J. Purtill

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


We investigated whether performing a repeat 2-stage exchange eradicates infection in patients who previously underwent 2-stage treatment for an infected total hip arthroplasty. We identified 15 patients who had failed a 2-stage total hip arthroplasty and underwent a planned repeat 2-stage between 2000 and 2009. Of the 15 patients, 8 were treated with a complete 2-stage procedure, whereas the remaining 7 patients were treated only with a first-stage resection of the infected implant. Of the 8 patients who underwent complete 2-stage exchange, 1 died because of in-hospital complications, and 1 had a recurrent infection. Repeat infection is highly associated with resistant organisms, obesity, and poor patient health. Of the 7 patients who underwent resection without reimplantation, 3 had a recurrent infection. Our data suggest that if infection can be adequately controlled after repeat resection of the joint prosthesis, reimplantation is a reasonable option.

Original languageEnglish
Pages (from-to)923-926.e1
JournalJournal of Arthroplasty
Issue number6
StatePublished - Jun 2012


  • 2-stage exchange hip arthroplasty
  • Periprosthetic joint infection
  • Recurrent PJI
  • Repeat 2-stage
  • Total hip arthroplasty


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