Renal vitamin D receptor expression and vitamin D renoprotection

Adriana S. Dusso

doi:10.1038/ki.2012.30

Renal vitamin D receptor expression and vitamin D renoprotection

Adriana S. Dusso

Division of Endocrinology, Metabolism & Lipid Research

Research output: Contribution to journal › Comment/debate

7 Scopus citations

Abstract

Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.

Original language	English
Pages (from-to)	937-939
Number of pages	3
Journal	Kidney International
Volume	81
Issue number	10
DOIs	https://doi.org/10.1038/ki.2012.30
State	Published - May 2 2012

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10.1038/ki.2012.30

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abstract = "Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.",

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AB - Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.

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Renal vitamin D receptor expression and vitamin D renoprotection

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