Renal tubular acidoses are disorders of tubular function with multiple etiologic and pathogenic mechanisms. Three distinct physiologic types (1, 2, and 4) are currently recognized clinically. They manifest as hyperchloremic metabolic acidosis with or without potassium homeostatic abnormalities. Type 1 is often associated with nephrolithiasis and nephrocalcinosis, both of which can be effectively managed by alkali therapy.
|Number of pages||19|
|Journal||Endocrinology and Metabolism Clinics of North America|
|State||Published - 1990|