Renal Trauma Increases Risk of Future Hypertension

E. Charles Osterberg, Mohannad A. Awad, Gregory P. Murphy, Thomas W. Gaither, Jennie Yoo, Jack W. McAninch, T. hanabhudee Chumnarnsongkhroh, Benjamin N. Breyer

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Objective: To determine if traumatic renal injuries or computed tomography (CT) findings are predictive of hypertension (HTN) development following injury. Methods: A retrospective review of a renal trauma database was performed from 1995 to 2015. Renal injuries were graded by the American Association for the Surgery of Trauma system, with high-grade defined as IV or V. Nonrenal genitourinary trauma (ie bladder, penile, urethral, and testicular) patients were selected as controls. Patients with a diagnosis of HTN before their trauma or those lacking follow-up were excluded. Risk factors associated with HTN following trauma were identified using multivariable regression with propensity scoring. Results: In total, 163 patients had a renal injury and 60 had nonrenal, genitourinary injuries. The median age was 31 years (interquartile range 23-43) with median follow-up of 4.7 years (interquartile range 1.9-8.5). Twenty-three (14%) patients with renal trauma were newly diagnosed with HTN on follow-up, compared with 2 (3%) in the control groups. (P =.02) After propensity quartile adjustment, patients with high-grade trauma had higher odds of developing HTN compared with low-grade renal trauma patients and controls (adjusted odds ratio 3.5, 95% confidence interval 1.3-9.3, P =.01). Patients with a midpole medial laceration and medial blood on CT had higher odds of developing HTN compared with patients without these characteristics (odds ratio 5.36, 95% confidence interval 1.3-22.6, P =.02). Conclusion: Increasing renal trauma grade is a risk factor for future development of HTN. CT findings at trauma presentation may be useful in stratifying patients who are at increased risk.

Original languageEnglish
Pages (from-to)198-204
Number of pages7
StatePublished - Jun 2018


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