Renal osteodystrophy

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Renal osteodystrophy is a general complication of chronic renal failure and end-stage renal disease. The nature of renal osteodystrophy has changed since osteomalacia due to aluminium intoxication has become less prevalent. Osteomalacia has been replaced by the adynamic bone disorder. Suppression of osteitis fibrosa, calcitriol and control of secondary hyperparathyroidism has been shown to produce the adynamic bone disorder. Thus, many other factors besides secondary hyperparathyroidism and calcitriol deficiency contribute to the pathogenesis of renal osteodystrophy. Some of these factors, according to our current state of knowledge, are discussed in this chapter along with the presentation and treatment of renal osteodystrophy.

Original languageEnglish
Pages (from-to)165-194
Number of pages30
JournalBailliere's Clinical Endocrinology and Metabolism
Issue number1
StatePublished - 1997


  • Adynamic bone disorder
  • Bone growth factors
  • Osteitis fibrosa
  • Osteomalacia
  • Secondary hyperparathyroidism


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