Renaissance of MMPs as therapeutic targets? Maybe

Gregory I. Goldberg

doi:10.1016/j.str.2014.12.003

Renaissance of MMPs as therapeutic targets? Maybe

Gregory I. Goldberg

Division of Dermatology

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

Matrix metalloproteases (MMPs) have been implicated in a number of different human diseases and are currently one of the actively pursued targets in drug discovery and development. In this issue of Structure, Udi and colleagues describe how an inhibitory antibody, LEM-2/15, affects a member of the MMP family, MT1-MMP.

Original language	English
Pages (from-to)	6-7
Number of pages	2
Journal	Structure
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/j.str.2014.12.003
State	Published - Jan 6 2015

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abstract = "Matrix metalloproteases (MMPs) have been implicated in a number of different human diseases and are currently one of the actively pursued targets in drug discovery and development. In this issue of Structure, Udi and colleagues describe how an inhibitory antibody, LEM-2/15, affects a member of the MMP family, MT1-MMP.",

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AB - Matrix metalloproteases (MMPs) have been implicated in a number of different human diseases and are currently one of the actively pursued targets in drug discovery and development. In this issue of Structure, Udi and colleagues describe how an inhibitory antibody, LEM-2/15, affects a member of the MMP family, MT1-MMP.

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Renaissance of MMPs as therapeutic targets? Maybe

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