TY - JOUR
T1 - Remission of longstanding metastatic paraganglioma in a patient after use of zoledronic acid
AU - Schutte, Justin
AU - Mardani, Mahta
AU - Weilbaecher, Katherine
AU - Prasad, Vikas
AU - Chrisinger, John S.A.
AU - Trikalinos, Nikolaos A.
N1 - Publisher Copyright:
© BMJ Publishing Group Limited 2024.
PY - 2024/11/28
Y1 - 2024/11/28
N2 - A patient with a long history of bone predominant, metastatic paraganglioma who had multiple episodes of progressive disease despite prior treatments demonstrated a remarkable disease response to zoledronic acid. After 1 year of treatment, there was a complete resolution of lymphadenopathy and disappearance of all somatostatin receptor avid lesions by positron emission tomography-CT and radiopharmaceutical Gallium Ga 68 Dotatate. Stability of disease was further demonstrated by CT over several years. The patient continues on surveillance.
AB - A patient with a long history of bone predominant, metastatic paraganglioma who had multiple episodes of progressive disease despite prior treatments demonstrated a remarkable disease response to zoledronic acid. After 1 year of treatment, there was a complete resolution of lymphadenopathy and disappearance of all somatostatin receptor avid lesions by positron emission tomography-CT and radiopharmaceutical Gallium Ga 68 Dotatate. Stability of disease was further demonstrated by CT over several years. The patient continues on surveillance.
KW - Calcium and bone
KW - Cancer - see Oncology
KW - Cancer intervention
KW - Oncology
KW - Therapeutic indications
UR - http://www.scopus.com/inward/record.url?scp=85211212779&partnerID=8YFLogxK
U2 - 10.1136/bcr-2024-262628
DO - 10.1136/bcr-2024-262628
M3 - Article
C2 - 39613415
AN - SCOPUS:85211212779
SN - 1757-790X
VL - 17
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 11
M1 - e262628
ER -