Remimazolam: The future of its sedative potential

Basavana Gouda Goudra, Preet Mohinder Singh

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations


Remimazolam (CNS 7056) is a new drug innovation in anesthesia. It combines the properties of two unique drugs already established in anesthesia - Midazolam and remifentanil. It acts on GABA receptors like midazolam and has organ-independent metabolism like remifentanil. It is likely to be the sedative of the future, as preliminary phase II trials have shown minimal residual effects on prolonged infusions. It has potential to be used as a sedative in ICU and as a novel agent for procedural sedation. Unlike most rapidly acting intravenous sedatives available presently, the propensity to cause apnea is very low. Availability of a specific antagonist (flumazenil) adds to its safety even in cases of overdose. The present review discusses remimazolam's potential as a new drug in anesthesia along with the presently available literary evidence.

Original languageEnglish
Pages (from-to)388-391
Number of pages4
JournalSaudi Journal of Anaesthesia
Issue number3
StatePublished - 2014


  • CNS 7056
  • newer sedatives in anesthesia
  • remimazolam
  • soft chemistry in anesthesia


Dive into the research topics of 'Remimazolam: The future of its sedative potential'. Together they form a unique fingerprint.

Cite this