Relation of meat, fat, and fiber intake to the risk of colon cancer in women

Jose A. Bufill, Saxon Graham, Mya Swanson, Jeffrey S. Bland, Alvin R. Loosli, Richard J. Calvert, Leon Prosky, Louise Acheson, Raymond R. White, Ray Baldwin, Walter C. Willett, Meir J. Stampfer, Graham A. Colditz, Bernard A. Rosner, Frank E. Speizer

Research output: Contribution to journalLetterpeer-review


To the Editor: In their study of dietary risk factors for colon cancer in women (Dec. 13, 1990, issue),1 Willett and colleagues should have reported the anatomical sites of the primary colon cancers in their patients. Data from diverse research perspectives suggest that knowing whether a colon cancer is proximal or distal to the splenic flexure may serve to identify categories of colon cancer with distinct pathogenetic mechanisms.2 This hypothesis may have particular relevance to women, in whom the incidence of proximal and distal tumors appears to vary with age. Distal tumors are more likely to develop in women under. . .

Original languageEnglish
Pages (from-to)199-202
Number of pages4
JournalNew England Journal of Medicine
Issue number3
StatePublished - Jan 16 1992


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