Relation of enzyme activity to local/global stability of murine adenosine deaminase: ¹⁹F NMR studies

Keyphrases

• 19F NMR 100%
• Enzyme Activity 100%
• NMR Studies 100%
• Adenosine Deaminase 100%
• Local & Global Stability 100%
• Urea 66%
• Tryptophan 66%
• Chemical Shift 66%
• 19F NMR Spectroscopy 66%
• Shift Change 66%
• Protein Folding 33%
• Conformational Change 33%
• Ligand Binding 33%
• Enzymatic Activity 33%
• Denaturants 33%
• Tertiary Structure 33%
• Substrate Analog 33%
• Structural Mechanism 33%
• Secondary Structure 33%
• Tryptophan Residues 33%
• Transition State Inhibitors 33%
• Inhibitor Binding 33%
• 19F NMR Spectra 33%
• Apparent Rate Constant 33%
• Chemical Environment 33%
• Urea Analogues 33%
• Catalytic Site 33%
• Global Stability 33%
• Conformational Flexibility 33%
• Local Region 33%
• Enzymatic Proteins 33%
• Immune Competence 33%
• Purine Metabolism 33%
• Local Stability 33%
• Change Information 33%
• Deoxycoformycin 33%
• Structure Transition 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme Activity 100%
• Murine 100%
• Adenosine Deaminase 100%
• Enzyme 75%
• Tryptophan 75%
• Nuclear Magnetic Resonance Spectroscopy 50%
• Protein Folding 25%
• Conformational Change 25%
• Ligand Binding 25%
• Tertiary Structure 25%
• Substrate Analog 25%
• Transition State Analog 25%
• Immunocompetence 25%
• Purine Metabolism 25%
• Pentostatin 25%

Immunology and Microbiology

• Enzyme Activity 100%
• Murine 100%
• Adenosine Deaminase 100%
• Tryptophan 75%
• Urea 75%
• Nuclear Magnetic Resonance Spectroscopy 50%
• Protein Folding 25%
• Conformational Transition 25%
• Immunocompetence 25%
• Purine Metabolism 25%
• Ligand Binding 25%
• Tertiary Structure 25%