Relation of defibrillatory potential minima to post-defibrillatory activation

Francis X. Witkowski; Patricia A. Penkoske

Relation of defibrillatory potential minima to post-defibrillatory activation

Francis X. Witkowski, Patricia A. Penkoske

Division of Critical Care

Research output: Contribution to conference › Paper › peer-review

5 Scopus citations

Abstract

Management of patients with malignant arrhythmias occurring outside the hospital and the development of clinically applicable systems for internal defibrillation have stimulated interest in the factors influencing cardiac defibrillation. Using a directly coupled (DC) electrode and amplification scheme, the authors have developed a system capable of simultaneous three-dimensional mapping of both the high energy shock field created in the heart by defibrillation electrodes in addition to the mapping of the immediate postshock myocardial activation sequence. Experiments performed in vivo in anesthetized open-chest dogs revealed that successful defibrillation required 100% of the site examined to be depolarized, with the first postdefibrillation beat originating in the area of minimum defibrillatory potential.

Original language	English
Pages	212-214
Number of pages	3
State	Published - Nov 1988
Event	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA Duration: Nov 4 1988 → Nov 7 1988

Conference

Conference	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
City	New Orleans, LA, USA
Period	11/4/88 → 11/7/88

Cite this

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title = "Relation of defibrillatory potential minima to post-defibrillatory activation",

abstract = "Management of patients with malignant arrhythmias occurring outside the hospital and the development of clinically applicable systems for internal defibrillation have stimulated interest in the factors influencing cardiac defibrillation. Using a directly coupled (DC) electrode and amplification scheme, the authors have developed a system capable of simultaneous three-dimensional mapping of both the high energy shock field created in the heart by defibrillation electrodes in addition to the mapping of the immediate postshock myocardial activation sequence. Experiments performed in vivo in anesthetized open-chest dogs revealed that successful defibrillation required 100% of the site examined to be depolarized, with the first postdefibrillation beat originating in the area of minimum defibrillatory potential.",

author = "Witkowski, {Francis X.} and Penkoske, {Patricia A.}",

note = "Copyright: Copyright 2004 Elsevier B.V., All rights reserved.; Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 04-11-1988 Through 07-11-1988",

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language = "English",

pages = "212--214",

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T1 - Relation of defibrillatory potential minima to post-defibrillatory activation

AU - Witkowski, Francis X.

AU - Penkoske, Patricia A.

PY - 1988/11

Y1 - 1988/11

N2 - Management of patients with malignant arrhythmias occurring outside the hospital and the development of clinically applicable systems for internal defibrillation have stimulated interest in the factors influencing cardiac defibrillation. Using a directly coupled (DC) electrode and amplification scheme, the authors have developed a system capable of simultaneous three-dimensional mapping of both the high energy shock field created in the heart by defibrillation electrodes in addition to the mapping of the immediate postshock myocardial activation sequence. Experiments performed in vivo in anesthetized open-chest dogs revealed that successful defibrillation required 100% of the site examined to be depolarized, with the first postdefibrillation beat originating in the area of minimum defibrillatory potential.

AB - Management of patients with malignant arrhythmias occurring outside the hospital and the development of clinically applicable systems for internal defibrillation have stimulated interest in the factors influencing cardiac defibrillation. Using a directly coupled (DC) electrode and amplification scheme, the authors have developed a system capable of simultaneous three-dimensional mapping of both the high energy shock field created in the heart by defibrillation electrodes in addition to the mapping of the immediate postshock myocardial activation sequence. Experiments performed in vivo in anesthetized open-chest dogs revealed that successful defibrillation required 100% of the site examined to be depolarized, with the first postdefibrillation beat originating in the area of minimum defibrillatory potential.

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M3 - Paper

AN - SCOPUS:0024112251

SP - 212

EP - 214

T2 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Y2 - 4 November 1988 through 7 November 1988

ER -

Relation of defibrillatory potential minima to post-defibrillatory activation

Abstract

Conference

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