Abnormal angiogenesis is a cardinal feature in the pathophysiology of several diseases of the retina including retinopathy of prematurity, diabetic retinopathy and choroidal neovascularization associated with age-related macular degeneration. Recent evidence has implicated macrophages as components of the innate immune system that play a key role in regulating angiogenesis in the retina and choroid. This review will focus on the role of macrophages in regulating ocular angiogenesis.
|Title of host publication||Retinal Degenerative Diseases|
|Subtitle of host publication||Laboratory and Therapeutic Investigations|
|Editors||Robert Anderson, Nawajes Mandal, Joe Hollyfield, Matthew LaVail|
|Number of pages||5|
|State||Published - Dec 1 2010|
|Name||Advances in Experimental Medicine and Biology|