Regulation of angiogenesis by macrophages

Research output: Chapter in Book/Report/Conference proceedingConference contribution

27 Scopus citations

Abstract

Abnormal angiogenesis is a cardinal feature in the pathophysiology of several diseases of the retina including retinopathy of prematurity, diabetic retinopathy and choroidal neovascularization associated with age-related macular degeneration. Recent evidence has implicated macrophages as components of the innate immune system that play a key role in regulating angiogenesis in the retina and choroid. This review will focus on the role of macrophages in regulating ocular angiogenesis.

Original languageEnglish
Title of host publicationRetinal Degenerative Diseases
Subtitle of host publicationLaboratory and Therapeutic Investigations
EditorsRobert Anderson, Nawajes Mandal, Joe Hollyfield, Matthew LaVail
Pages15-19
Number of pages5
DOIs
StatePublished - Dec 1 2010

Publication series

NameAdvances in Experimental Medicine and Biology
Volume664
ISSN (Print)0065-2598

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  • Cite this

    Apte, R. S. (2010). Regulation of angiogenesis by macrophages. In R. Anderson, N. Mandal, J. Hollyfield, & M. LaVail (Eds.), Retinal Degenerative Diseases: Laboratory and Therapeutic Investigations (pp. 15-19). (Advances in Experimental Medicine and Biology; Vol. 664). https://doi.org/10.1007/978-1-4419-1399-9_2