Regramming myeloid responses to improve cancer immunotherapy

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Infiltration by immunosuppressive myeloid cells helps tumors to overcome immune surveillance and can render patients less responsive to therapeutic intervention. Several recent studies have demonstrated that reprogramming myeloid responses can effectively enhance cancer immunotherapy, suggesting several new potential combination therapies for clinical testing.

Original languageEnglish
JournalOncoImmunology
Volume4
Issue number6
DOIs
StatePublished - Jan 1 2015

Keywords

  • Cancer immunotherapy
  • Immune checkpoints
  • MDSCs
  • Macrophages
  • PD-1

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