Regional myocardial stress distribution from magnetic resonance image-based mathematical models

John S. Pirolo, Lawrence L. Creswell, Stephen J. Bresina, William H. Perman, Barna A. Szabo, Kent W. Myers, Michael W. Vannier, Michael K. Pasque

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The instantaneous regional stress distribution within the myocardium, which cannot be directly measured, has been estimated using improved numerical methods and nonaxisymmetric biventricular geometry. To do this, we have employed computer-aided solid mathematical modeling to generate a three-dimensional representation for an ex vivo canine biventricular unit using magnetic resonance imaging. A two-dimensional transverse section was isolated from the solid mathematical model for regional stress analysis using p-version finite element analysis. Loading conditions and material property descriptions were taken from published reports. Analyses showed the maximum principal stresses to range from -1.76 × 105 to 8.52 × 105 dynes/cm2 during systolic loading, and from -3.85 × 104 to 1.13 × 105 dynes/cm2 during diastolic loading. This study demonstrates that magnetic resonance image-based solid mathematical biventricular models are suitable for regional stress analysis using p-version finite element analysis, p-Version finite element analysis using magnetic resonance image-based cardiac representations facilitates in vivo stress-strain analyses and may allow the clinical estimation of regional myocardial stress.

Original languageEnglish
Pages (from-to)276-284
Number of pages9
JournalThe Annals of thoracic surgery
Volume52
Issue number2
DOIs
StatePublished - Aug 1991

Fingerprint

Dive into the research topics of 'Regional myocardial stress distribution from magnetic resonance image-based mathematical models'. Together they form a unique fingerprint.

Cite this