Refractive index matching of tissue components as a new technology for correlation and diffusing-photon spectroscopy and imaging

V. V. Tuchin, J. Culver, C. Cheung, S. A. Tatarkova, M. A. Della Vecchia, D. Zimnyakov, A. Chaussky, A. G. Yodh, B. Chance

Research output: Contribution to journalConference articlepeer-review

15 Scopus citations

Abstract

The refractive index matching of components of highly scattering tissue has a strong influence on its transmittance and reflectance what can be considered as a new tool for imaging within relatively thick tissues. We present experimental data on various solutions, gels and oils influence on optical properties of in vitro human eye and in vivo human skin. The dynamics of tissue optical properties depending on matter diffusion rate within tissue is studied. The possible application of refractive index matching effect for diffusing-photon imaging is discussed.

Original languageEnglish
Pages (from-to)111-120
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3598
StatePublished - Jan 1 1999
Externally publishedYes
EventProceedings of the 1999 Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III - San Jose, CA, USA
Duration: Jan 27 1999Jan 29 1999

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