Refining the nuclear auxin response pathway through structural biology

David A. Korasick, Joseph M. Jez, Lucia C. Strader

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Auxin is a key regulator of plant growth and development. Classical molecular and genetic techniques employed over the past 20 years identified the major players in auxin-mediated gene expression and suggest a canonical auxin response pathway. In recent years, structural and biophysical studies clarified the molecular details of auxin perception, the recognition of DNA by auxin transcription factors, and the interaction of auxin transcription factors with repressor proteins. These studies refine the auxin signal transduction model and raise new questions that increase the complexity of auxin signaling.

Original languageEnglish
Pages (from-to)22-28
Number of pages7
JournalCurrent Opinion in Plant Biology
StatePublished - Oct 1 2015


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