TY - JOUR
T1 - Refining the nuclear auxin response pathway through structural biology
AU - Korasick, David A.
AU - Jez, Joseph M.
AU - Strader, Lucia C.
N1 - Funding Information:
Support from the National Science Foundation Graduate Research Fellowship Program ( 2011101911 to D.A.K.), the United States Department of Agriculture – National Institute of Food and Agriculture Fellowship Program ( MOW-2014-01877 to D.A.K.), the National Institutes of Health ( R00 GM089987-03 to L.C.S.), and the National Science Foundation ( MCB-1157771 to J.M.J. and IOS-1453750 to L.C.S.) is acknowledged.
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Auxin is a key regulator of plant growth and development. Classical molecular and genetic techniques employed over the past 20 years identified the major players in auxin-mediated gene expression and suggest a canonical auxin response pathway. In recent years, structural and biophysical studies clarified the molecular details of auxin perception, the recognition of DNA by auxin transcription factors, and the interaction of auxin transcription factors with repressor proteins. These studies refine the auxin signal transduction model and raise new questions that increase the complexity of auxin signaling.
AB - Auxin is a key regulator of plant growth and development. Classical molecular and genetic techniques employed over the past 20 years identified the major players in auxin-mediated gene expression and suggest a canonical auxin response pathway. In recent years, structural and biophysical studies clarified the molecular details of auxin perception, the recognition of DNA by auxin transcription factors, and the interaction of auxin transcription factors with repressor proteins. These studies refine the auxin signal transduction model and raise new questions that increase the complexity of auxin signaling.
UR - http://www.scopus.com/inward/record.url?scp=84930958935&partnerID=8YFLogxK
U2 - 10.1016/j.pbi.2015.05.007
DO - 10.1016/j.pbi.2015.05.007
M3 - Review article
C2 - 26048079
AN - SCOPUS:84930958935
SN - 1369-5266
VL - 27
SP - 22
EP - 28
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
ER -