Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation

Keyphrases

• Inflammasome Activation 100%
• Streptolysin O 100%
• Pore-forming Activity 100%
• Interleukin-1β 80%
• Pore-forming Toxins 80%
• Macrophages 60%
• Pore Formation 60%
• Pyroptosis 60%
• Immune Response 20%
• Red Blood Cells 20%
• Plasma Membrane 20%
• Mutagenesis 20%
• Cytokine Production 20%
• Mammalian Cells 20%
• Less Toxic 20%
• Bacterial Cells 20%
• Active Site mutant 20%
• NLRP3 Inflammasome 20%
• Plasma Membrane Repair 20%
• Direct Killing 20%
• Cell Lysis 20%
• Direct Toxicity 20%
• Pathogenic Effects 20%
• Direct Lysis 20%
• Equivalent number 20%
• Adjuvant Activity 20%
• NLRP3 Activation 20%
• Formation Control 20%

Biochemistry, Genetics and Molecular Biology

• Streptolysin 100%
• Inflammasome 100%
• Interleukin-1 80%
• Pore-Forming Toxin 80%
• Channel Gating 60%
• Macrophage 60%
• Pyroptosis 60%
• Secretion (Process) 40%
• Cell Membrane 40%
• Wild Type 20%
• Immune Response 20%
• Mutagenesis 20%
• Cytokine Production 20%
• NLRP3 Inflammasome 20%
• Cytolysis 20%
• NLR Family Pyrin Domain containing 3 20%

Immunology and Microbiology

• Streptolysin 100%
• Inflammasome 100%
• Interleukin 1 80%
• Macrophage 60%
• Channel Gating 60%
• Pyroptosis 60%
• Secretion (Process) 40%
• Cell Membrane 40%
• Wild Type 20%
• Immune Response 20%
• Cytokine Production 20%
• Mutagenesis 20%
• NLRP3 Inflammasome 20%
• Cytolysis 20%
• Erythrocyte 20%
• NLRP3 20%