Keyphrases
AMPA Receptor (AMPAR)
100%
Antagonism
100%
Auditory Nerve
100%
GluA2
100%
Nerve Excitability
100%
Methyl
88%
Amino
88%
Ca2+
66%
Compound Action Potential
33%
Auditory Nerve Fibers
33%
Afferent Synapse
33%
IEM-1925
33%
Intracochlear Delivery
33%
Guinea pig
22%
Systemic Delivery
22%
Receptor Subunits
22%
Trauma
11%
Safety Profile
11%
Glutamate Excitotoxicity
11%
Synapse
11%
Inner Hair Cell
11%
Increased Safety
11%
Action Potential Threshold
11%
Cochlear Function
11%
Perilymph
11%
Metabolically Stable
11%
Distortion Product Otoacoustic Emission (DPOAE)
11%
Cochlear Nerve
11%
Compound Potency
11%
Blood Levels
11%
Local Delivery
11%
Pharmacokinetic Properties
11%
Nerve Activity
11%
IC50
11%
Baseline Measurements
11%
Channel Conductance
11%
Elimination Half-life
11%
Hearing Function
11%
Off-target Binding
11%
Glutamatergic Synaptic Transmission
11%
Potential Reduction
11%
Acoustic Overexposure
11%
Ca2+ Permeability
11%
Heart Rate Monitoring
11%
Threshold Product
11%
Neuroscience
AMPA Receptor
100%
Cochlea
100%
Nerve Excitability
100%
Receptor
100%
Synapse
66%
Action Potential
50%
Sensation of Hearing
50%
Nerve Fiber
50%
Receptor Subunit
33%
Excitotoxicity
16%
Glutamic Acid
16%
In Vivo
16%
In Vitro
16%
Nerve Conduction
16%
Synaptic Transmission
16%
Cochlear Nerve
16%
Pharmacokinetics
16%
Medicine and Dentistry
Calcium Ion
100%
AMPA Receptor
100%
Nerve Excitability
100%
Receptor
75%
Cochlea
75%
Synapse
50%
Nerve Fiber
37%
Action Potential
37%
Receptor Subunit
25%
Injury
12%
In Vitro
12%
Cochlear Nerve
12%
Distortion Product Otoacoustic Emission
12%
Pharmacokinetics
12%
Synaptic Transmission
12%
Binding Assay
12%
Perilymph
12%
Nerve Conduction
12%
IC50
12%
Inner Hair Cell
12%
Elimination Half-Life
12%
Glutamate Excitotoxicity
12%
Tetramer
12%
Pharmacology, Toxicology and Pharmaceutical Science
Calcium Ion
100%
AMPA Receptor
100%
Receptor
75%
Receptor Subunit
25%
Guinea Pig
25%
Injury
12%
Elimination
12%
Glutamic Acid
12%
IC50
12%
Tetramer
12%
Excitotoxicity
12%
Pharmacokinetics
12%