Reduced field-of-view diffusion-weighted imaging of the brain at 7 T

Cornelius von Morze, Douglas A.C. Kelley, Timothy M. Shepherd, Suchandrima Banerjee, Duan Xu, Christopher P. Hess

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Ventral and rostral regions of the brain are of emerging importance for the MRI characterization of early dementia, traumatic brain injury and epilepsy. Unfortunately, standard single-shot echo planar diffusion-weighted imaging of these regions at high fields is contaminated by severe imaging artifacts in the vicinity of air-tissue interfaces. To mitigate these artifacts and improve visualization of the temporal and frontal lobes at 7 T, we applied a reduced field-of-view strategy, enabled by outer volume suppression (OVS) with novel quadratic phase radiofrequency (RF) pulses, combined with partial Fourier and parallel imaging methods. The new acquisition greatly reduced the level of artifacts in six human subjects (including four patients with early symptoms of dementia).

Original languageEnglish
Pages (from-to)1541-1545
Number of pages5
JournalMagnetic Resonance Imaging
Issue number10
StatePublished - Dec 2010


  • Brain
  • Diffusion-weighted imaging
  • Field of view


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