Recurrent Proximal Junctional Kyphosis: Incidence, Risk Factors, Revision Rates, and Outcomes at 2-Year Minimum Follow-up

Han Jo Kim, Shan Jin Wang, Renaud Lafage, Sravisht Iyer, Christopher Shaffrey, Gregory Mundis, Richard Hostin, Douglas Burton, Christopher Ames, Eric Klineberg, Munish Gupta, Justin Smith, Frank Schwab, Virginie Lafage

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Study Design.Retrospective comparative cohort study.Objective.Assess the incidence, risk factors, and outcomes of recurrent proximal junctional kyphosis (r-PJK) in PJK revision patients.Summary of Background Data.Several studies have identified the incidence and risk factors for PJK after primary surgery. However, few studies have reported on PJK recurrence after revision for PJK.Methods.A multicenter database of patients who underwent PJK revision surgery with minimum 2-year follow-up was analyzed. Demographic, operative, and radiographic outcomes were compared in patients with r-PJK and patients without recurrence no-Proximal Junctional Kyphosis (n-PJK). Postoperative Scoliosis Research Society-22r, Short Form-36, and Oswestry Disability Index were compared. Preoperative and most recent spinopelvic, cervical, and cervicothoracic radiographic parameters were compared. Univariate and multivariate analyses were used to determine r-PJK risk factors. A predictive model was formulated based on our logistic regression analysis.Results.A total of 70 patients met the inclusion criteria with an average follow-up of 21.8 months. The mean age was 66.3±9.4 and 80% of patients were women. Before revision, patients had a proximal junctional angle angle of -31.7°±15.9°. The rate of recurrent PJK was 44.3%. Logistic regression showed that pre-revision thoracic pelvic angle (odds ratio [OR]: 1.060 95% confidence interval [CI] 1.002; 1.121; P=0.042) and prerevision C2-T3 sagittal vertical axis (SVA; OR: 1.040 95% CI [1.007; 1.073] P=0.016) were independent predictors of r-PJK. Classification with these parameters yielded an accuracy of 72.7%, precision of 80.6%, and recall of 73.5%. When examining correction, or change in alignment with revision surgery, we found that change in SVA (OR: 0.981 95% CI [0.968; 0.994] P=0.005) was the only predictor of r-PJK with accuracy of 66.7%, precision of 74.2%, and recall of 69.7%.Conclusion.Patients after PJK revision surgery had a recurrence rate of 44%. Logistic regression based on the prerevision variables showed that prerevision thoracic pelvic angle and prerevision C2-T3 SVA were independent predictors of r-PJK.Level of Evidence: 4.

Original languageEnglish
Pages (from-to)E18-E24
JournalSpine
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2020

Keywords

  • C2-T3 sagittal vertical axis
  • complications
  • proximal junctional kyphosis
  • recurrent proximal junctional kyphosis
  • spine deformity
  • spine revision
  • thoracic pelvic angle

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