AIDS is frequently complicated by mucosal infections with Candida species. Oral candidiasis is usually a mild illness but may be complicated by severe pain, esophagitis, and nutritional wasting. Recurrent oral candidiasis occurs in as many as 80% of patients with AIDS. Clinical response rates to topical or systemic antifungal agents are between 65% and 100%. The optimal strategy for the use of prophylactic antifungal therapy is unclear. Chronic administration of antifungal agents must be balanced with issues of compliance, cost, quality of life, and the emergence of resistant strains of Candida.
|Journal||Infections in Medicine|
|State||Published - Jan 1 1994|
- acquired immune deficiency syndrome (AIDS)
- candidiasis, oral
- human immunodeficiency virus (HIV)
- infection, fungal