PURPOSE: We studied a case of chronic, recurrent, bilateral, corneal ulcerations associated with smokeable methamphetamine abuse, commonly known as 'ice,' in an otherwise healthy 31-year-old woman. METHODS: Every few months the patient had recurrent corneal ulcerations. Each time, she was hospitalized and treated successfully with topical antibiotics. RESULTS: Even though she had undergone numerous formal attempts at drug rehabilitation, she continued to have relapses, and ulceration recurred only during periods of smokeable methamphetamine abuse. CONCLUSION: Illicit use of smokeable methamphetamine may result in corneal ulceration.