TY - JOUR
T1 - Recent applications of circular dichroism to structural problems, especially oligosaccharide structures
AU - Nakanishi, Koji
AU - Kuroyanagi, Masanori
AU - Nambu, Hirofumi
AU - Oltz, Eugene M.
AU - Takeda, Reiji
AU - Verdine, Gregory L.
AU - Zask, Arie
N1 - Funding Information:
Acknowledgements - We are indebted to Dr. H.—W. Liu and other colleagues, Drs. M. DiNovi, J. Furukawa, 3. Golik, M. Nakatani, R.J. Stonard and D.A. Trainor, who were involved in the early stages of this study (see references cited). These studies are supported by a grant from the National Inst itues of Health (CA 11572)
PY - 1984/1/1
Y1 - 1984/1/1
N2 - First, a brief review of the exciton chirality method is given, with emphasis on practical aspects. This is followed by a case (mitomycin C) in which the interpretation of CD data is purposely carried out in a wavelength region where undesirable interchromophoric interaction is negligible. A new chromophore for coupled CD studies and the additivity relation in coupled CD is mentioned. Generalized schemes for carrying out micro- (**) scale structural studies of oligosaccharides, namely identification of sugars and their glycosidic linkages, are described. The simple three-step sequence currently under study is based on the remarkable additivity relationship found in the coupled CD of pyranose p-methoxycarbonyl benzyl ethers.
AB - First, a brief review of the exciton chirality method is given, with emphasis on practical aspects. This is followed by a case (mitomycin C) in which the interpretation of CD data is purposely carried out in a wavelength region where undesirable interchromophoric interaction is negligible. A new chromophore for coupled CD studies and the additivity relation in coupled CD is mentioned. Generalized schemes for carrying out micro- (**) scale structural studies of oligosaccharides, namely identification of sugars and their glycosidic linkages, are described. The simple three-step sequence currently under study is based on the remarkable additivity relationship found in the coupled CD of pyranose p-methoxycarbonyl benzyl ethers.
UR - http://www.scopus.com/inward/record.url?scp=0021470584&partnerID=8YFLogxK
U2 - 10.1351/pac198456081031
DO - 10.1351/pac198456081031
M3 - Article
AN - SCOPUS:0021470584
VL - 56
SP - 1031
EP - 1048
JO - Pure and Applied Chemistry
JF - Pure and Applied Chemistry
SN - 0033-4545
IS - 8
ER -