Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019

Michael Browning; Cameron S. Carter; Christopher Chatham; Hanneke Den Ouden; Claire M. Gillan; Justin T. Baker; Adam M. Chekroud; Roshan Cools; Peter Dayan; James Gold; Rita Z. Goldstein; Catherine A. Hartley; Adam Kepecs; Rebecca P. Lawson; Janaina Mourao-Miranda; Mary L. Phillips; Diego A. Pizzagalli; Albert Powers; David Rindskopf; Jonathan P. Roiser; Katharina Schmack; Daniela Schiller; Miriam Sebold; Klaas Enno Stephan; Michael J. Frank; Quentin Huys; Martin Paulus

doi:10.1016/j.biopsych.2019.12.026

Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019

Michael Browning, Cameron S. Carter, Christopher Chatham, Hanneke Den Ouden, Claire M. Gillan, Justin T. Baker, Adam M. Chekroud, Roshan Cools, Peter Dayan, James Gold, Rita Z. Goldstein, Catherine A. Hartley, Adam Kepecs, Rebecca P. Lawson, Janaina Mourao-Miranda, Mary L. Phillips, Diego A. Pizzagalli, Albert Powers, David Rindskopf, Jonathan P. RoiserKatharina Schmack, Daniela Schiller, Miriam Sebold, Klaas Enno Stephan, Michael J. Frank, Quentin Huys, Martin Paulus

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Original language	English
Pages (from-to)	e5-e10
Journal	Biological Psychiatry
Volume	88
Issue number	2
DOIs	https://doi.org/10.1016/j.biopsych.2019.12.026
State	Published - Jul 15 2020

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10.1016/j.biopsych.2019.12.026

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Browning, M., Carter, C. S., Chatham, C., Den Ouden, H., Gillan, C. M., Baker, J. T., Chekroud, A. M., Cools, R., Dayan, P., Gold, J., Goldstein, R. Z., Hartley, C. A., Kepecs, A., Lawson, R. P., Mourao-Miranda, J., Phillips, M. L., Pizzagalli, D. A., Powers, A., Rindskopf, D., ... Paulus, M. (2020). Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019. Biological Psychiatry, 88(2), e5-e10. https://doi.org/10.1016/j.biopsych.2019.12.026

@article{62c0f69d98d443548b786595998a525f,

title = "Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019",

author = "Michael Browning and Carter, {Cameron S.} and Christopher Chatham and {Den Ouden}, Hanneke and Gillan, {Claire M.} and Baker, {Justin T.} and Chekroud, {Adam M.} and Roshan Cools and Peter Dayan and James Gold and Goldstein, {Rita Z.} and Hartley, {Catherine A.} and Adam Kepecs and Lawson, {Rebecca P.} and Janaina Mourao-Miranda and Phillips, {Mary L.} and Pizzagalli, {Diego A.} and Albert Powers and David Rindskopf and Roiser, {Jonathan P.} and Katharina Schmack and Daniela Schiller and Miriam Sebold and Stephan, {Klaas Enno} and Frank, {Michael J.} and Quentin Huys and Martin Paulus",

note = "Funding Information: This work was supported by the Medical Research Council Clinician Scientist Fellowship (Grant No. MR/N008103/1 [to MB]), National Institute for Health Research Oxford Health Biomedical Research Centre (MB), Max Planck Society (to PD), National Institutes of Health (Grant Nos. 1R01DA041528 , 1R01DA047851 , and 1R01AT010627 [to RZG]), National Institute on Drug Abuse Small Business Innovation Research Phase I subcontract to Soterix Medical (Grant No. 271201800035C [to RZG]), Wellcome Trust (Grant No. WT102845/Z/13/Z [to JM-M]), National Institute of Mental Health K23 Career Development Award (Grant No. K23 MH115252-01A1 [to AP]), Burroughs-Wellcome Fund Career Award for Medical Scientists (to AP), Ren{\'e} and Susanne Braginsky Foundation (to KES), and National Institute of General Medical Sciences (Grant No. P20GM121312 [to MP]). The Banbury Center Meeting was funded by grants from the Society for Biological Psychiatry, William K. Warren Foundation , and Robert J. & Nancy D. Carney Institute for Brain Science at Brown University . Funding Information: This work was supported by the Medical Research Council Clinician Scientist Fellowship (Grant No. MR/N008103/1 [to MB]), National Institute for Health Research Oxford Health Biomedical Research Centre (MB), Max Planck Society (to PD), National Institutes of Health (Grant Nos. 1R01DA041528, 1R01DA047851, and 1R01AT010627 [to RZG]), National Institute on Drug Abuse Small Business Innovation Research Phase I subcontract to Soterix Medical (Grant No. 271201800035C [to RZG]), Wellcome Trust (Grant No. WT102845/Z/13/Z [to JM-M]), National Institute of Mental Health K23 Career Development Award (Grant No. K23 MH115252-01A1 [to AP]), Burroughs-Wellcome Fund Career Award for Medical Scientists (to AP), Ren? and Susanne Braginsky Foundation (to KES), and National Institute of General Medical Sciences (Grant No. P20GM121312 [to MP]). The Banbury Center Meeting was funded by grants from the Society for Biological Psychiatry, William K. Warren Foundation, and Robert J. & Nancy D. Carney Institute for Brain Science at Brown University. We thank John Krystal, M.D. Bruce Cuthbert, M.D. Anne Churchland, Ph.D. and Michele Ferrante, Ph.D. for invaluable discussion and advice. MB has received travel expenses from Lundbeck for attending conferences and acted as a consultant for Janssen Research and the Centre for Human Drug Research. CC is a full-time employee of Hoffman La Roche. HDO has acted as a consultant for Lundbeck Pharmaceuticals. JTB has received consulting fees from Pear Therapeutics, BlackThorn Therapeutics, Niraxx Therapeutics, and AbleTo, Inc. AMC holds equity in Spring Care, Inc. Fitbit, Inc. and UnitedHealthcare, Inc.; is lead inventor on three patent submissions relating to treatment for major depressive disorder (U.S. Patent and Trademark Office Docket No, Y0087.70116US00, U.S. Patent and Trademark Office provisional application 62/491,660, and USPTO provisional application 62/629,041); and has consulted for Fortress Biotech, Inc. on antidepressant drug development. JG receives royalty payments from the Brief Assessment of Cognition in Schizophrenia. Over the past 3 years, MLP has received an honorarium from Sunovion Pharmaceuticals. Over the past 3 years, DAP has received consulting fees from Akili Interactive Labs, BlackThorn Therapeutics, Boehringer Ingelheim, Compass, Posit Science, and Takeda Pharmaceuticals and an honorarium from Alkermes for activities unrelated to the current article. JPR has acted as a consultant for Cambridge Cognition, Takeda, and GE Healthcare. MJF is a consultant for Hoffman La Roche. MP is an advisor to Spring Care, Inc. and he has received royalties for an article about methamphetamine in UpToDate. The other authors report no biomedical financial interests or potential conflicts of interest.",

year = "2020",

month = jul,

day = "15",

doi = "10.1016/j.biopsych.2019.12.026",

language = "English",

volume = "88",

pages = "e5--e10",

journal = "Biological Psychiatry",

issn = "0006-3223",

number = "2",

}

Browning, M, Carter, CS, Chatham, C, Den Ouden, H, Gillan, CM, Baker, JT, Chekroud, AM, Cools, R, Dayan, P, Gold, J, Goldstein, RZ, Hartley, CA, Kepecs, A, Lawson, RP, Mourao-Miranda, J, Phillips, ML, Pizzagalli, DA, Powers, A, Rindskopf, D, Roiser, JP, Schmack, K, Schiller, D, Sebold, M, Stephan, KE, Frank, MJ, Huys, Q & Paulus, M 2020, 'Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019', Biological Psychiatry, vol. 88, no. 2, pp. e5-e10. https://doi.org/10.1016/j.biopsych.2019.12.026

TY - JOUR

T1 - Realizing the Clinical Potential of Computational Psychiatry

T2 - Report From the Banbury Center Meeting, February 2019

AU - Browning, Michael

AU - Carter, Cameron S.

AU - Chatham, Christopher

AU - Den Ouden, Hanneke

AU - Gillan, Claire M.

AU - Baker, Justin T.

AU - Chekroud, Adam M.

AU - Cools, Roshan

AU - Dayan, Peter

AU - Gold, James

AU - Goldstein, Rita Z.

AU - Hartley, Catherine A.

AU - Kepecs, Adam

AU - Lawson, Rebecca P.

AU - Mourao-Miranda, Janaina

AU - Phillips, Mary L.

AU - Pizzagalli, Diego A.

AU - Powers, Albert

AU - Rindskopf, David

AU - Roiser, Jonathan P.

AU - Schmack, Katharina

AU - Schiller, Daniela

AU - Sebold, Miriam

AU - Stephan, Klaas Enno

AU - Frank, Michael J.

AU - Huys, Quentin

AU - Paulus, Martin

N1 - Funding Information: This work was supported by the Medical Research Council Clinician Scientist Fellowship (Grant No. MR/N008103/1 [to MB]), National Institute for Health Research Oxford Health Biomedical Research Centre (MB), Max Planck Society (to PD), National Institutes of Health (Grant Nos. 1R01DA041528 , 1R01DA047851 , and 1R01AT010627 [to RZG]), National Institute on Drug Abuse Small Business Innovation Research Phase I subcontract to Soterix Medical (Grant No. 271201800035C [to RZG]), Wellcome Trust (Grant No. WT102845/Z/13/Z [to JM-M]), National Institute of Mental Health K23 Career Development Award (Grant No. K23 MH115252-01A1 [to AP]), Burroughs-Wellcome Fund Career Award for Medical Scientists (to AP), René and Susanne Braginsky Foundation (to KES), and National Institute of General Medical Sciences (Grant No. P20GM121312 [to MP]). The Banbury Center Meeting was funded by grants from the Society for Biological Psychiatry, William K. Warren Foundation , and Robert J. & Nancy D. Carney Institute for Brain Science at Brown University . Funding Information: This work was supported by the Medical Research Council Clinician Scientist Fellowship (Grant No. MR/N008103/1 [to MB]), National Institute for Health Research Oxford Health Biomedical Research Centre (MB), Max Planck Society (to PD), National Institutes of Health (Grant Nos. 1R01DA041528, 1R01DA047851, and 1R01AT010627 [to RZG]), National Institute on Drug Abuse Small Business Innovation Research Phase I subcontract to Soterix Medical (Grant No. 271201800035C [to RZG]), Wellcome Trust (Grant No. WT102845/Z/13/Z [to JM-M]), National Institute of Mental Health K23 Career Development Award (Grant No. K23 MH115252-01A1 [to AP]), Burroughs-Wellcome Fund Career Award for Medical Scientists (to AP), Ren? and Susanne Braginsky Foundation (to KES), and National Institute of General Medical Sciences (Grant No. P20GM121312 [to MP]). The Banbury Center Meeting was funded by grants from the Society for Biological Psychiatry, William K. Warren Foundation, and Robert J. & Nancy D. Carney Institute for Brain Science at Brown University. We thank John Krystal, M.D. Bruce Cuthbert, M.D. Anne Churchland, Ph.D. and Michele Ferrante, Ph.D. for invaluable discussion and advice. MB has received travel expenses from Lundbeck for attending conferences and acted as a consultant for Janssen Research and the Centre for Human Drug Research. CC is a full-time employee of Hoffman La Roche. HDO has acted as a consultant for Lundbeck Pharmaceuticals. JTB has received consulting fees from Pear Therapeutics, BlackThorn Therapeutics, Niraxx Therapeutics, and AbleTo, Inc. AMC holds equity in Spring Care, Inc. Fitbit, Inc. and UnitedHealthcare, Inc.; is lead inventor on three patent submissions relating to treatment for major depressive disorder (U.S. Patent and Trademark Office Docket No, Y0087.70116US00, U.S. Patent and Trademark Office provisional application 62/491,660, and USPTO provisional application 62/629,041); and has consulted for Fortress Biotech, Inc. on antidepressant drug development. JG receives royalty payments from the Brief Assessment of Cognition in Schizophrenia. Over the past 3 years, MLP has received an honorarium from Sunovion Pharmaceuticals. Over the past 3 years, DAP has received consulting fees from Akili Interactive Labs, BlackThorn Therapeutics, Boehringer Ingelheim, Compass, Posit Science, and Takeda Pharmaceuticals and an honorarium from Alkermes for activities unrelated to the current article. JPR has acted as a consultant for Cambridge Cognition, Takeda, and GE Healthcare. MJF is a consultant for Hoffman La Roche. MP is an advisor to Spring Care, Inc. and he has received royalties for an article about methamphetamine in UpToDate. The other authors report no biomedical financial interests or potential conflicts of interest.

PY - 2020/7/15

Y1 - 2020/7/15

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U2 - 10.1016/j.biopsych.2019.12.026

DO - 10.1016/j.biopsych.2019.12.026

M3 - Letter

C2 - 32113656

AN - SCOPUS:85086574751

SN - 0006-3223

VL - 88

SP - e5-e10

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 2

ER -

Realizing the Clinical Potential of Computational Psychiatry: Report From the Banbury Center Meeting, February 2019

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